Determination of 1,2-Benzisothiazolin-3-One in Paper for Food Packaging by Fluorescence Spectroscopy

A novel method has been developed to detect 1,2-benzisothiazolin-3-one (BIT) in paper for food packaging by hydrothermal extraction coupled with fluorescence spectroscopy in paper for food package. Parameters affecting fluorescence intensity have been evaluated, including the pH of solvents and the effect of surfactants. It turned out to be that fluorescent spectroscopy was a sensitive and easy method to determine BIT in paper package. The regression equation obtained was liner, and the correction coefficient was 99.9%, the limit detection (LOD) was 25.3μg/L, method detection limit (MDL) was 0.25mg/kg, which turned out that this method was sensitive and precise to determine BIT in food package.