Neutral red as a specific light-up fluorescent probe for i-motif DNA

Neutral red as a specific light-up fluorescent probe for i-motif DNA

We report a specific light-up fluorescent probe for i-motif DNA for the first time. Compared with the previously reported probes, neutral red could selectively interact with an i-motif and show a significant increase in its fluorescence. This feature makes it advantageous for designing label-free fl...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (99), p.14330-14333
Hauptverfasser: Xu, Lijun, Wang, Jine, Sun, Na, Liu, Min, Cao, Yi, Wang, Zhili, Pei, Renjun
Format: Artikel
Sprache:eng
Schlagworte:
Deoxyribonucleic acid
Detection
Fluorescence
Fluorescent Dyes - chemistry
Humans
Neutral Red - chemistry
Nucleotide Motifs
Telomere - chemistry
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Zusammenfassung:We report a specific light-up fluorescent probe for i-motif DNA for the first time. Compared with the previously reported probes, neutral red could selectively interact with an i-motif and show a significant increase in its fluorescence. This feature makes it advantageous for designing label-free fluorescent sensing systems.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc07674b