Synthesis and antifungal activity of 3-substituted imidazo[1,2-b][1,2,4,5]tetrazines

Synthesis and antifungal activity of 3-substituted imidazo[1,2-b][1,2,4,5]tetrazines

A number of new 3-substituted imidazo[1,2- b ][1,2,4,5]tetrazines containing azolyl, aminopyridyl, and alkoxyl substituents was synthesized. These compounds were studied for the biological activity against mycelial anthropophilic and zoophilous dermatophyte fungi ( Trichophyton, Microsporum and Epid...

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Veröffentlicht in:Russian chemical bulletin 2015-09, Vol.64 (9), p.2100-2105
Hauptverfasser: Ishmetova, R. I., Ignatenko, N. K., Belyaninova, I. A., Tolshchina, S. G., Korotina, A. V., Slepukhin, P. A., Evstigneeva, N. P., Zil’berberg, N. V., Amineva, P. G., Kungurov, N. V., Rusinov, G. L., Chupakhin, O. N.
Format: Artikel
Sprache:eng
Schlagworte:
Candida
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Epidermophyton
Full Articles
Inorganic Chemistry
Microsporum
Organic Chemistry
Trichophyton
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Zusammenfassung:A number of new 3-substituted imidazo[1,2- b ][1,2,4,5]tetrazines containing azolyl, aminopyridyl, and alkoxyl substituents was synthesized. These compounds were studied for the biological activity against mycelial anthropophilic and zoophilous dermatophyte fungi ( Trichophyton, Microsporum and Epidermophyton ), causing diseases of skin and its appendages (hair, nails), and yeast-like fungi Candida .
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-015-1124-y