Bendiocarb induced histopathological and biochemical alterations in rat liver and Preventive role of vitamins C and E

Highlights • Effects of bendiocarp on liver were studied in rats. • Bendiocarp treatment increased the antioxidant enzyme of oxidative stress biomarkers. • Bendiocarp treatment caused several histopathological changes in rats. • Vitamins C and E protect liver tissues.

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Bibliographische Detailangaben
Veröffentlicht in:	Environmental toxicology and pharmacology 2017-01, Vol.49, p.148-155
Hauptverfasser:	Apaydin, Fatma Gökçe, Baş, Hatice, Kalender, Suna, Kalender, Yusuf
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Antioxidants - pharmacology Ascorbic acid Ascorbic Acid - pharmacology Bendiocarb Body weight Catalase - metabolism Emergency Enzymatic activity Glutathione Peroxidase - metabolism Glutathione Transferase - metabolism Histopathology Insecticides - toxicity Lipid peroxidation Lipid Peroxidation - drug effects Liver Liver - drug effects Liver - pathology Liver toxicity Male Malondialdehyde Oxidative stress Parameters Peroxidation Phenylcarbamates - toxicity Rats, Wistar Rodents Statistical analysis Studies Superoxide Dismutase - metabolism Tocopherol Toxicity Vitamin C Vitamin E Vitamin E - pharmacology Vitamins Vitamins - pharmacology
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Beschreibung
Zusammenfassung:	Highlights • Effects of bendiocarp on liver were studied in rats. • Bendiocarp treatment increased the antioxidant enzyme of oxidative stress biomarkers. • Bendiocarp treatment caused several histopathological changes in rats. • Vitamins C and E protect liver tissues.
ISSN:	1382-6689 1872-7077
DOI:	10.1016/j.etap.2016.11.018