Effects of ABCB1 Genetic Polymorphism on the Oral Absorption of Losartan

Effects of ABCB1 Genetic Polymorphism on the Oral Absorption of Losartan

Losartan and its active metabolite E-3174 samples in plasma and urine were collected up to 10 and 8 hours after drug administration, and the concentrations of both samples were determined by the HPLC method.

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Veröffentlicht in:Clinical therapeutics 2016-10, Vol.38 (10), p.e22-e22
Hauptverfasser: Byeon, J.Y, Kim, D.H, Lim, H.J, Lee, C.M, Kim, Y.H, Lee, S.Y
Format: Artikel
Sprache:eng
Schlagworte:
Haplotypes
Internal Medicine
Medical Education
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Zusammenfassung:Losartan and its active metabolite E-3174 samples in plasma and urine were collected up to 10 and 8 hours after drug administration, and the concentrations of both samples were determined by the HPLC method.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2016.07.139