Molecular characterization of multidrug-resistant (MDR) Pseudomonas aeruginosa isolated in a burn center

Highlights • Two new P. aeruginosa STs displaying carbapenems resistance. • STs with different pathogenic potential: biofilm production and exoU presence. • β-Lactamase production was not the major cause of carbapenems resistance. • Biofilm production in Clone A may explain its persistence in this u...

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Veröffentlicht in:	Burns 2017-02, Vol.43 (1), p.137-143
Hauptverfasser:	de Almeida Silva, Keila de Cássia Ferreira, Calomino, Mariana Alcântara, Deutsch, Gabriela, de Castilho, Selma Rodrigues, de Paula, Geraldo Renato, Esper, Luciana Maria Ramires, Teixeira, Lenise Arneiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacterial Proteins beta-Lactam Resistance - genetics beta-Lactamases - genetics Biofilm Biofilms Brazil Burn Units Burns - microbiology Carbapenem resistant Carbapenems Critical Care Drug Resistance, Multiple, Bacterial - genetics Genotype Humans Microbial Sensitivity Tests Multidrug resistant Multilocus Sequence Typing Polymerase Chain Reaction Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - growth & development Pseudomonas Infections - microbiology Wound burn
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Zusammenfassung:	Highlights • Two new P. aeruginosa STs displaying carbapenems resistance. • STs with different pathogenic potential: biofilm production and exoU presence. • β-Lactamase production was not the major cause of carbapenems resistance. • Biofilm production in Clone A may explain its persistence in this unit.
ISSN:	0305-4179 1879-1409
DOI:	10.1016/j.burns.2016.07.002