CD4 Counts in Laboratory Monitoring of HIV Disease—Experience from Western India

CD4 Counts in Laboratory Monitoring of HIV Disease—Experience from Western India

Background: CD4 counts vary in different populations. The present study was conducted to determine CD4 counts in different World Health Organization (WHO) clinical stages in antiretroviral therapy naïve individuals and to find out optimum CD4 cutoffs. Method: Data of adult HIV seropositive patients...

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Veröffentlicht in:Journal of the International Association of Providers of AIDS Care 2014-07, Vol.13 (4), p.324-327
Hauptverfasser: Ingole, Nayana, Nataraj, Gita, Mehta, Preeti, Paranjpe, Supriya, Sarkate, Purva
Format: Artikel
Sprache:eng
Schlagworte:
Acquired immune deficiency syndrome
Adult
AIDS
Antiretroviral drugs
Antiretroviral therapy
CD4 Lymphocyte Count
Cross-Sectional Studies
Disease
Female
HIV
HIV Infections - ethnology
HIV Infections - immunology
Human immunodeficiency virus
Humans
Immunosuppression
India
Lymphocyte Count
Male
Patients
ROC Curve
Severity of Illness Index
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Zusammenfassung:Background: CD4 counts vary in different populations. The present study was conducted to determine CD4 counts in different World Health Organization (WHO) clinical stages in antiretroviral therapy naïve individuals and to find out optimum CD4 cutoffs. Method: Data of adult HIV seropositive patients who underwent CD4 count and total lymphocyte count (TLC) testing were included for analysis. The severity of immunosuppression was graded based on WHO criteria. To establish optimum CD4 cutoff values, receiver–operator characteristics (ROC) curves were generated. Results: Of 754 patients, 52.2% had CD4 counts
ISSN:2325-9574
2325-9582
2325-9582
DOI:10.1177/2325957412474846