Addition of adjuvant progesterone to physical-exam-indicated cervical cerclage to prevent preterm birth

Addition of adjuvant progesterone to physical-exam-indicated cervical cerclage to prevent preterm birth

Aim The aim of this study was to assess the effect of vaginal progesterone as an adjuvant therapy to physical‐exam‐indicated cervical cerclage (PEICC). Methods This retrospective cohort study included 53 consecutive singleton women who underwent PEICC because of acute cervical insufficiency at 17–24...

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Veröffentlicht in:The journal of obstetrics and gynaecology research 2016-12, Vol.42 (12), p.1666-1672
Hauptverfasser: Jung, Eun Young, Oh, Kyung Joon, Hong, Joon-Seok, Han, Bo Ryoung, Joo, Jung Kyung
Format: Artikel
Sprache:eng
Schlagworte:
adjuvant therapy
Adult
Birth
Birth weight
Cerclage, Cervical
cervical cerclage
cervical insufficiency
Female
Gestational Age
Health risk assessment
Humans
Intensive care
Neonates
Physical Examination
Population studies
Pregnancy
Pregnancy Outcome
Premature birth
Premature Birth - drug therapy
Premature Birth - prevention & control
Premature Birth - surgery
Progesterone
Progesterone - administration & dosage
Progesterone - therapeutic use
Retrospective Studies
spontaneous preterm birth
Sutures
Treatment Outcome
Vagina
vaginal progesterone
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Zusammenfassung:Aim The aim of this study was to assess the effect of vaginal progesterone as an adjuvant therapy to physical‐exam‐indicated cervical cerclage (PEICC). Methods This retrospective cohort study included 53 consecutive singleton women who underwent PEICC because of acute cervical insufficiency at 17–24 gestational weeks. The study population was divided into two groups: the adjuvant progesterone group (n = 18) and the non‐adjuvant group (n = 35). A 200‐mg dose of vaginal micronized natural progesterone was administered after cerclage in the adjuvant progesterone group. Primary outcome measure was spontaneous preterm birth (SPTB) at
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.13128