Imaging findings in faciobrachial dystonic seizures associated with LGI-1 antibodies

A 76-year-old woman presented with a three-month history of faciobrachial dystonic seizures associated with cognitive impairment and hyponatremia. Cerebrospinal fluid analysis was unremarkable. A whole-body CT scan demonstrated no malignancies. Brain MRI revealed involvement of the mesial right temp...

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Veröffentlicht in:	Arquivos de neuro-psiquiatria 2016-11, Vol.74 (11), p.947-947
Hauptverfasser:	Grativvol, Ronnyson Susano, Simabukuro, Mateus Mistieri, Spera, Raphael Ribeiro, Cavalcante, Wagner Cid Palmeira, Araújo, Hugo Henrique Soares, Sakuno, Daniel, Lucato, Leandro Tavares, Pinto, Lécio Figueira, Castro, Luiz Henrique Martins, Nitrini, Ricardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cognitive Dysfunction - complications Dystonic Disorders - complications Dystonic Disorders - diagnostic imaging Female Humans IMAGES IN NEUROLOGY Magnetic Resonance Imaging Proteins - immunology Seizures - diagnostic imaging
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Zusammenfassung:	A 76-year-old woman presented with a three-month history of faciobrachial dystonic seizures associated with cognitive impairment and hyponatremia. Cerebrospinal fluid analysis was unremarkable. A whole-body CT scan demonstrated no malignancies. Brain MRI revealed involvement of the mesial right temporal lobe, right striatum and globus pallidus and bilateral supratentorial white matter (Figures A, B, C). Leucine-rich glioma inactivated protein 1 (LGI-1) antibodies were detected in the serum.
ISSN:	0004-282X 1678-4227 1678-4227 0004-282X
DOI:	10.1590/0004-282X20160146