FEBS letters

The binding constants of the alpha(1)-foetoprotein of the rat embryo serum for oestrone and oestradiol-17beta have similar values, i.e. 1 x 10(8) M(-1) in average at 25 degrees. There is probably one binding site per mole of binding protein. The high alpha(1)-foetoprotein concentration in the rat em...

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Veröffentlicht in:FEBS letters 1972-04, Vol.22 (1), p.113-116
Hauptverfasser: Savu, L, Crepy, O, Guerin, M A, Nunez, E, Engelmann, F, Benassayag, C, Jayle, M F
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Sprache:fre
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Zusammenfassung:The binding constants of the alpha(1)-foetoprotein of the rat embryo serum for oestrone and oestradiol-17beta have similar values, i.e. 1 x 10(8) M(-1) in average at 25 degrees. There is probably one binding site per mole of binding protein. The high alpha(1)-foetoprotein concentration in the rat embryo serum at 17-19 days of pregnancy explains the exceptionally high levels of fixation of the phenolsteroids by this serum.
ISSN:1873-3468