Synthesis of Dihydroisoxazole Nucleoside and Nucleotide Analogs

Synthesis of Dihydroisoxazole Nucleoside and Nucleotide Analogs

The dihydroisoxazole nucleosides as well as their phosphonate derivatives were efficiently prepared via 1,3-dipolar cycloaddition reactions of nitrile oxides with corresponding vinyl nucleoside bases for antiviral studies.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of organic chemistry 1997-01, Vol.62 (1), p.88-92
Hauptverfasser: Gi, Hung-Jang, Xiang, Yuejun, Schinazi, Raymond F, Zhao, Kang
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The dihydroisoxazole nucleosides as well as their phosphonate derivatives were efficiently prepared via 1,3-dipolar cycloaddition reactions of nitrile oxides with corresponding vinyl nucleoside bases for antiviral studies.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo961779r