The Vinylogous Aldol Reaction:  A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver

Relevant applications of the vinylogous aldol reaction in synthesis and in natural product chemistry are highlighted. Mannich-type reactions, basically isosteric modifications of the aldol theme, are included.

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Veröffentlicht in:Chemical reviews 2000-06, Vol.100 (6), p.1929-1972
Hauptverfasser: Casiraghi, Giovanni, Zanardi, Franca, Appendino, Giovanni, Rassu, Gloria
Format: Artikel
Sprache:eng
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Zusammenfassung:Relevant applications of the vinylogous aldol reaction in synthesis and in natural product chemistry are highlighted. Mannich-type reactions, basically isosteric modifications of the aldol theme, are included.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr990247i