Septal scopolamine-systemic diazepam interaction in passive avoidance learning in rats

The role of the septal region in passive avoidance (step-through) learning was studied by administering 15µg/0.5µl of scopolamine intraseptally to rats, together with an i.p. injection of 2mg/kg of diazepam to the same animals. The combined treatment provoked a severe impairment in retention of the...

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Veröffentlicht in:Behavioural pharmacology 1996-12, Vol.7 (8), p.827-829
Hauptverfasser: Anglade, F., Galey, D., Chapouthier, G.
Format: Artikel
Sprache:eng
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Zusammenfassung:The role of the septal region in passive avoidance (step-through) learning was studied by administering 15µg/0.5µl of scopolamine intraseptally to rats, together with an i.p. injection of 2mg/kg of diazepam to the same animals. The combined treatment provoked a severe impairment in retention of the learning situation, whereas animals which received either scopolamine or diazepam alone did not show any deficit.
ISSN:1473-5849