The effects of chronic hepatitis C and B virus infections on liver reduced and oxidized glutathione concentrations

The effects of chronic hepatitis C and B virus infections on liver reduced and oxidized glutathione concentrations

The aim of this study was to evaluate the effects of hepatitis B and C virus infections on liver glutathione status. Reduced and oxidized glutathione levels were determined in liver biopsy specimens obtained from patients with chronic liver disease including chronic active hepatitis and cirrhosis. I...

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Veröffentlicht in:Hepatology research 2000-08, Vol.18 (2), p.104-109
Hauptverfasser: Tanyalcin, Tijen, Taskiran, Dilek, Topalak, Omer, Batur, Yucel, Kutay, Fatma
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Chronic hepatitis
Glutathione
Human viral diseases
Infectious diseases
Liver
Medical sciences
Viral diseases
Viral hepatitis
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Zusammenfassung:The aim of this study was to evaluate the effects of hepatitis B and C virus infections on liver glutathione status. Reduced and oxidized glutathione levels were determined in liver biopsy specimens obtained from patients with chronic liver disease including chronic active hepatitis and cirrhosis. In patients with hepatitis B virus infections, GSH and GSH/GSSG levels were significantly low compared with those in controls ( P
ISSN:1386-6346
1872-034X
DOI:10.1016/S1386-6346(99)00088-1