Instrumentation and Methodology for Simultaneous Excitation/Detection of Ions in an FTICR Mass Spectrometer

A method for direct and continuous detection of ion motion during different perturbation events of the fourier transform ion cyclotron resonance (FTICR) experiment is demonstrated. The modifications necessary to convert an ordinary FTICR cell into one capable of performing simultaneous excitation/de...

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Veröffentlicht in:Analytical chemistry (Washington) 2000-08, Vol.72 (15), p.3568-3572
Hauptverfasser: Schmidt, Eric G, Fiorentino, Michael A, Arkin, C Richard, Laude, D. A
Format: Artikel
Sprache:eng
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Zusammenfassung:A method for direct and continuous detection of ion motion during different perturbation events of the fourier transform ion cyclotron resonance (FTICR) experiment is demonstrated. The modifications necessary to convert an ordinary FTICR cell into one capable of performing simultaneous excitation/detection (SED) using a capacitive network are outlined. With these modifications, a 200-fold reduction in the detection of the coupled excitation signal is achieved. This allows the unique ability not only to observe the response to the perturbation but to observe the perturbation event itself. SED is used successfully to monitor the ion cyclotron transient during single-frequency excitation, remeasurement and excite−τ−excite experiments.
ISSN:0003-2700
1520-6882
DOI:10.1021/ac000104s