Concerted Catalytic Reactions for Conversion of Ketones or Enol Acetates to Chiral Acetates

Concerted Catalytic Reactions for Conversion of Ketones or Enol Acetates to Chiral Acetates

Enol acetates or ketones asymmetrically transformed to chiral acetates in high yields with high optical purities through multistep reactions catalyzed by a lipase and a ruthenium complex. 2,6-Dimethylheptan-4-ol was chosen as a suitable hydrogen donor, and 4-chlorophenyl acetate was used as an acyl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2000-02, Vol.2 (3), p.409-411
Hauptverfasser: Jung, Hyun M, Koh, Jeong H, Kim, Mahn-Joo, Park, Jaiwook
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Enol acetates or ketones asymmetrically transformed to chiral acetates in high yields with high optical purities through multistep reactions catalyzed by a lipase and a ruthenium complex. 2,6-Dimethylheptan-4-ol was chosen as a suitable hydrogen donor, and 4-chlorophenyl acetate was used as an acyl donor for the conversion of ketones.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol9914043