Hyperthermia-induced changes in the vascular permeability of rats: a model system to examine therapeutic interventions

Extravasation in the heart, liver, lung, kidney, spleen, gastrocnemius, and duodenum was quantified in normothermic and hyperthermic (core temperature ( T c)=41.5, 42, or 42.6°C) rats. Following attainment of the target T c, Evans blue (Eb) was administered via jugular cannula; the animals were anes...

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Veröffentlicht in:	Journal of thermal biology 2000-10, Vol.25 (5), p.381-386
Hauptverfasser:	Matthew, Candace B., DuBose, David A., Sils, Ingrid V., Tartartini, Kimberly A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Core temperature Endothelium Evans blue Extravasation Hyperthermia Rats Thermoregulation Vascular permeability
Online-Zugang:	Volltext
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