11-Isopropylcryptolepine: A Novel Alkaloid Isolated from Cryptolepis sanguinolenta Characterized Using Submicro NMR Techniques
A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a m...
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| Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 1999-02, Vol.62 (2), p.238-240 |
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| container_end_page | 240 |
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| container_issue | 2 |
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| container_title | Journal of natural products (Washington, D.C.) |
| container_volume | 62 |
| creator | Hadden, Chad E Sharaf, Maged H. M Guido, Jane E Robins, Russell H Tackie, Albert N Phoebe, Charles H Schiff, Paul L Martin, Gary E |
| description | A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid. |
| doi_str_mv | 10.1021/np980278t |
| format | Article |
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M ; Guido, Jane E ; Robins, Russell H ; Tackie, Albert N ; Phoebe, Charles H ; Schiff, Paul L ; Martin, Gary E</creator><creatorcontrib>Hadden, Chad E ; Sharaf, Maged H. M ; Guido, Jane E ; Robins, Russell H ; Tackie, Albert N ; Phoebe, Charles H ; Schiff, Paul L ; Martin, Gary E</creatorcontrib><description>A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). 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M</creatorcontrib><creatorcontrib>Guido, Jane E</creatorcontrib><creatorcontrib>Robins, Russell H</creatorcontrib><creatorcontrib>Tackie, Albert N</creatorcontrib><creatorcontrib>Phoebe, Charles H</creatorcontrib><creatorcontrib>Schiff, Paul L</creatorcontrib><creatorcontrib>Martin, Gary E</creatorcontrib><title>11-Isopropylcryptolepine: A Novel Alkaloid Isolated from Cryptolepis sanguinolenta Characterized Using Submicro NMR Techniques</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid.</description><subject>alkaloids</subject><subject>Biological and medical sciences</subject><subject>chemical constituents of plants</subject><subject>chemical structure</subject><subject>Cryptolepis sanguinolenta</subject><subject>General pharmacology</subject><subject>Medical sciences</subject><subject>nuclear magnetic resonance spectroscopy</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>spectral analysis</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNpt0M1uEzEUBeARAtFQWPAC4AVIsBjwz8zYZhdFhVZqS0WStXXteFK3E3uwJ6hhBUtekyfB1USBBSvL8qfre05RPCf4HcGUvPe9FJhyMTwoJqSmuGwwrR8WE0waVjLRVEfFk5RuMMYMy_pxcUQw5jWv5KT4SUh5lkIfQ7_rTNz1Q-hs77z98PvHLzRFl-Gb7dC0u4UuuBXKtIPBrlAbwwbNDj6hBH69dT7f_ABodg0RzGCj-57xMjm_RvOt3jgTA7q8-IIW1lx793Vr09PiUQtdss_253Gx_HiymJ2W558_nc2m5yVUuBpKS43R2ugWcKUBCDDDNQMLDbWV1kwzXmspOKUYaGNkzYTQ0K6AtKLWrWHHxZtxbs56_--gNi4Z23XgbdgmRUQtqZSN5Jm-HWneNqVoW9VHt4G4UwSr-8bVofFsX-zH5nh29Y8cK87g1R5AMtC1Ebxx6a_jFeUNzawcmUuDvTs8Q7xVDc_Z1OJqrurTxQWmV0SJ7F-OvoWgYB3zyOWcYsIwFbLOy2XxehRgkroJ2-hzvf9J8AcBdLDR</recordid><startdate>19990201</startdate><enddate>19990201</enddate><creator>Hadden, Chad E</creator><creator>Sharaf, Maged H. 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M ; Guido, Jane E ; Robins, Russell H ; Tackie, Albert N ; Phoebe, Charles H ; Schiff, Paul L ; Martin, Gary E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a404t-e2ccbbcbfa04baa1a3c7b3aea62e4bb3b375b987220a26c95388bafda1f85bfc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>alkaloids</topic><topic>Biological and medical sciences</topic><topic>chemical constituents of plants</topic><topic>chemical structure</topic><topic>Cryptolepis sanguinolenta</topic><topic>General pharmacology</topic><topic>Medical sciences</topic><topic>nuclear magnetic resonance spectroscopy</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>spectral analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hadden, Chad E</creatorcontrib><creatorcontrib>Sharaf, Maged H. M</creatorcontrib><creatorcontrib>Guido, Jane E</creatorcontrib><creatorcontrib>Robins, Russell H</creatorcontrib><creatorcontrib>Tackie, Albert N</creatorcontrib><creatorcontrib>Phoebe, Charles H</creatorcontrib><creatorcontrib>Schiff, Paul L</creatorcontrib><creatorcontrib>Martin, Gary E</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hadden, Chad E</au><au>Sharaf, Maged H. M</au><au>Guido, Jane E</au><au>Robins, Russell H</au><au>Tackie, Albert N</au><au>Phoebe, Charles H</au><au>Schiff, Paul L</au><au>Martin, Gary E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>11-Isopropylcryptolepine: A Novel Alkaloid Isolated from Cryptolepis sanguinolenta Characterized Using Submicro NMR Techniques</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>1999-02-01</date><risdate>1999</risdate><volume>62</volume><issue>2</issue><spage>238</spage><epage>240</epage><pages>238-240</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>10075749</pmid><doi>10.1021/np980278t</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0163-3864 |
| ispartof | Journal of natural products (Washington, D.C.), 1999-02, Vol.62 (2), p.238-240 |
| issn | 0163-3864 1520-6025 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1859299697 |
| source | American Chemical Society Journals |
| subjects | alkaloids Biological and medical sciences chemical constituents of plants chemical structure Cryptolepis sanguinolenta General pharmacology Medical sciences nuclear magnetic resonance spectroscopy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments spectral analysis |
| title | 11-Isopropylcryptolepine: A Novel Alkaloid Isolated from Cryptolepis sanguinolenta Characterized Using Submicro NMR Techniques |
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