11-Isopropylcryptolepine: A Novel Alkaloid Isolated from Cryptolepis sanguinolenta Characterized Using Submicro NMR Techniques

A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a m...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1999-02, Vol.62 (2), p.238-240
Hauptverfasser:	Hadden, Chad E, Sharaf, Maged H. M, Guido, Jane E, Robins, Russell H, Tackie, Albert N, Phoebe, Charles H, Schiff, Paul L, Martin, Gary E
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaloids Biological and medical sciences chemical constituents of plants chemical structure Cryptolepis sanguinolenta General pharmacology Medical sciences nuclear magnetic resonance spectroscopy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments spectral analysis
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Beschreibung
Zusammenfassung:	A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np980278t