Matrix pathobiology—central roles for proteoglycans and heparanase in health and disease

This thematic minireview series highlights new concepts in matrix pathobiology. The reviews in this series cover the roles of the two matrix proteoglycans, decorin and biglycan, in inflammation and autophagy, the various functions of syndecans in cancer development and prognosis and the recently dis...

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Veröffentlicht in:	The FEBS journal 2017-01, Vol.284 (1), p.7-9
1. Verfasser:	Karamanos, Nikos K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Biglycan - metabolism Cancer Decorin Decorin - metabolism Extracellular Matrix - metabolism Glucuronidase - metabolism Humans Neoplasms - metabolism Neoplasms - pathology Phagocytosis Proteoglycans Reviews Syndecan Syndecans - metabolism
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Beschreibung
Zusammenfassung:	This thematic minireview series highlights new concepts in matrix pathobiology. The reviews in this series cover the roles of the two matrix proteoglycans, decorin and biglycan, in inflammation and autophagy, the various functions of syndecans in cancer development and prognosis and the recently discovered mechanisms underlying the multiple roles of heparanase in cancer progression, inflammation and autophagy.
ISSN:	1742-464X 1742-4658
DOI:	10.1111/febs.13945