Mining ancient proteins for next-generation drugs

Mining ancient proteins for next-generation drugs

Predicting the evolutionary ancestors of a protein drug provides a strategy for optimizing its pharmaceutical properties.

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Bibliographische Detailangaben
Veröffentlicht in:Nature biotechnology 2017-01, Vol.35 (1), p.28-29
Hauptverfasser: Lazarus, Robert A, Scheiflinger, Friedrich
Format: Artikel
Sprache:eng
Schlagworte:
631/114/469
631/61/338/469
Agriculture
Amino acid sequencing
Bioinformatics
Biomedical Engineering/Biotechnology
Biomedicine
Biotechnology
Data mining
Drug discovery
Drug therapy
Hormones
Life Sciences
Methods
Molecular biology
news-and-views
Proteins
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Beschreibung
Zusammenfassung:Predicting the evolutionary ancestors of a protein drug provides a strategy for optimizing its pharmaceutical properties.
ISSN:1087-0156
1546-1696
DOI:10.1038/nbt.3762