Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of poly...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (88), p.12952-12955
Hauptverfasser: Isahak, Naatasha, Gody, Guillaume, Malins, Lara R, Mitchell, Nicholas J, Payne, Richard J, Perrier, Sébastien
Format: Artikel
Sprache:eng
Schlagworte:
Addition polymerization
Chains (polymeric)
Concerts
Monomers
Peptides
Polymers
Rafts
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc06010b