Gd-Hybridized Plasmonic Au-Nanocomposites Enhanced Tumor-Interior Drug Permeability in Multimodal Imaging-Guided Therapy

Gd-Hybridized Plasmonic Au-Nanocomposites Enhanced Tumor-Interior Drug Permeability in Multimodal Imaging-Guided Therapy

An original gadolinium‐hybridized plasmonic gold nanocomposite is fabricated to provide an insightful and attractive strategy to overcome both the physiological and pathological barriers of tumor, and increase the transportation and permeability of imaging agents and drugs in tumor interior for achi...

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Veröffentlicht in:Advanced materials (Weinheim) 2016-10, Vol.28 (40), p.8950-8958
Hauptverfasser: Wang, Jing, Liu, Jing, Liu, Ying, Wang, Liming, Cao, Mingjing, Ji, Yinglu, Wu, Xiaochun, Xu, Yingying, Bai, Bing, Miao, Qing, Chen, Chunying, Zhao, Yuliang
Format: Artikel
Sprache:eng
Schlagworte:
drug delivery
Drugs
enhanced pathological permeability
gold nanocomposites
Imaging
multimodal imaging
Nanocomposites
Permeability
Plasmonics
Strategy
Transportation
tumor penetration
Tumors
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Zusammenfassung:An original gadolinium‐hybridized plasmonic gold nanocomposite is fabricated to provide an insightful and attractive strategy to overcome both the physiological and pathological barriers of tumor, and increase the transportation and permeability of imaging agents and drugs in tumor interior for achieving high‐sensitive multimodal imaging and simultaneously improving the therapeutic efficacy of cancer.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201603114