Dual-affinity peptide mediated inter-protein recognition

We present for the first time an enhanced interaction affinity between an abundant soluble protein (human serum albumin) and a membrane protein (chemokine receptor 4) mediated by a dual-affinity peptide E5.

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Bibliographische Detailangaben
Veröffentlicht in:	Organic & biomolecular chemistry 2016-01, Vol.14 (48), p.11342-11346
Hauptverfasser:	Duan, Hongyang, Zhu, Ling, Hou, Jingfei, Peng, Jiaxi, Xie, Hanyi, Lin, Yuchen, Liu, Changliang, Li, Wenzhe, Xu, Haiyan, Wang, Chen, Yang, Yanlian
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Peptides - chemistry Receptors, CXCR4 - chemistry Serum Albumin - chemistry
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	We present for the first time an enhanced interaction affinity between an abundant soluble protein (human serum albumin) and a membrane protein (chemokine receptor 4) mediated by a dual-affinity peptide E5.
ISSN:	1477-0520 1477-0539
DOI:	10.1039/c6ob02292h