Development of an enantioseparation method for novel psychoactive drugs by HPLC using a Lux® Cellulose-2 column in polar organic phase mode

Development of an enantioseparation method for novel psychoactive drugs by HPLC using a Lux® Cellulose-2 column in polar organic phase mode

Highlights • New chiral HPLC separation method applicable for a broad spectrum of NPDs. • A Lux® Cellulose-2 column was used in polar organic phase mode. • 40 psychoactive compounds were separated into their enantiomers, successfully. • Analysis of real life samples seized by Austrian police. • All...

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Veröffentlicht in:Forensic science international 2017-01, Vol.270, p.232-240
Hauptverfasser: Taschwer, Magdalena, Grascher, Jörg, Schmid, Martin G
Format: Artikel
Sprache:eng
Schlagworte:
Amphetamines
Capillary electrophoresis
Cellulose
Chlorinated polysaccharide-based stationary phase
Chromatography
Drugs
Enantioseparation
Experiments
Forensic sciences
HPLC
Ions
Methods
Novel psychoactive drugs (NPDs)
Pathology
Psychotropic drugs
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creator Taschwer, Magdalena
Grascher, Jörg
Schmid, Martin G
description Highlights • New chiral HPLC separation method applicable for a broad spectrum of NPDs. • A Lux® Cellulose-2 column was used in polar organic phase mode. • 40 psychoactive compounds were separated into their enantiomers, successfully. • Analysis of real life samples seized by Austrian police. • All tested compounds are traded as racemic mixtures.
doi_str_mv 10.1016/j.forsciint.2016.10.011
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source ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland
subjects Amphetamines
Capillary electrophoresis
Cellulose
Chlorinated polysaccharide-based stationary phase
Chromatography
Drugs
Enantioseparation
Experiments
Forensic sciences
HPLC
Ions
Methods
Novel psychoactive drugs (NPDs)
Pathology
Psychotropic drugs
title Development of an enantioseparation method for novel psychoactive drugs by HPLC using a Lux® Cellulose-2 column in polar organic phase mode
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