Aberrant spontaneous low-frequency brain activity in amnestic mild cognitive impairment: A meta-analysis of resting-state fMRI studies

Highlights • We performed a meta-analysis of ALFF changes in 14 datasets on aMCI. • Widespread aberrant regional spontaneous brain activity was observed in aMCI. • The aberrant regions involved in the default mode, salience, and visual networks. • GM volume corrections partly influenced the results...

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Veröffentlicht in:	Ageing research reviews 2017-05, Vol.35, p.12-21
Hauptverfasser:	Pan, PingLei, Zhu, Lin, Yu, TingTing, Shi, HaiCun, Zhang, Bing, Qin, Ruomeng, Zhu, Xiaolei, Qian, Lai, Zhao, Hui, Zhou, Hong, Xu, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnesia - diagnosis Amnesia - etiology Brain - physiopathology Brain Mapping - methods Cognitive Dysfunction - complications Cognitive Dysfunction - diagnosis Cognitive Dysfunction - physiopathology Female Humans Internal Medicine Magnetic Resonance Imaging - methods Male Neurology
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Beschreibung
Zusammenfassung:	Highlights • We performed a meta-analysis of ALFF changes in 14 datasets on aMCI. • Widespread aberrant regional spontaneous brain activity was observed in aMCI. • The aberrant regions involved in the default mode, salience, and visual networks. • GM volume corrections partly influenced the results of the ALFF analysis.
ISSN:	1568-1637 1872-9649
DOI:	10.1016/j.arr.2016.12.001