The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double‐blind, randomized trial

Objective To investigate whether a probiotic mix has additional effects when compared with an isolated dietary intervention on the body composition, lipid profile, endotoxemia, inflammation, and antioxidant profile. Methods Women who had excess weight or obesity were recruited to a randomized, doubl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Obesity (Silver Spring, Md.) Md.), 2017-01, Vol.25 (1), p.30-38
Hauptverfasser: Gomes, Aline Corado, de Sousa, Rávila Graziany Machado, Botelho, Patrícia Borges, Gomes, Tatyanne Letícia Nogueira, Prada, Patrícia Oliveira, Mota, João Felipe
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 38
container_issue 1
container_start_page 30
container_title Obesity (Silver Spring, Md.)
container_volume 25
creator Gomes, Aline Corado
de Sousa, Rávila Graziany Machado
Botelho, Patrícia Borges
Gomes, Tatyanne Letícia Nogueira
Prada, Patrícia Oliveira
Mota, João Felipe
description Objective To investigate whether a probiotic mix has additional effects when compared with an isolated dietary intervention on the body composition, lipid profile, endotoxemia, inflammation, and antioxidant profile. Methods Women who had excess weight or obesity were recruited to a randomized, double‐blind trial and received a probiotic mix (Lactobacillus acidophilus and casei; Lactococcus lactis; Bifidobacterium bifidum and lactis; 2 × 1010 colony‐forming units/day) (n = 21) or placebo (n = 22) for 8 weeks. Both groups received a dietary prescription. Body composition was assessed by anthropometry and dual‐energy X‐ray absorptiometry. The lipid profile, lipid accumulation product, plasma fatty acids, lipopolysaccharide, interleukin‐6, interleukin‐10, tumor necrosis factor‐α, adiponectin, and the antioxidant enzymes activities were analyzed. Results In comparison with the dietary intervention group, the dietary intervention + probiotic mix group showed a greater reduction in the waist circumference (−3.40% vs. −5.48%, P = 0.03), waist‐height ratio (−3.27% vs. −5.00%, P = 0.02), conicity index (−2.43% vs. −4.09% P = 0.03), and plasma polyunsaturated fatty acids (5.65% vs. −18.63%, P = 0.04) and an increase in the activity of glutathione peroxidase (−16.67% vs. 15.62%, P 
doi_str_mv 10.1002/oby.21671
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1852784505</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1852784505</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3881-6be27ecc3c25fdb80abaabf938c1a8fab06a28a11270baec024cb36f0fe091b03</originalsourceid><addsrcrecordid>eNp10ctKxDAUBuAgiveFLyABNwrOeJJO24w7FW8guFBBV-XkhpG2GZsWHd34CD6jT2KcqgvBRThZfOeHw0_IBoMhA-B7Xk6HnGU5myPLbJzAIE_Gt_O_f8GWyEoIDwCjDFK2SJa4ABB5Csvk9freUNTatc7XWFJjrVFtoN5SpJPGS-dbp2jlnqmvKUrtK_flULuJD66dUqx1fHH92ek46VWLbRf26QHVvpOl-Xh7l6Wr9S5tIo3rL0bTtnFYrpEFi2Uw699zldycHF8fnQ0uLk_Pjw4uBioRgg0yaXhulEoUT62WAlAiSjtOhGIoLErIkAtkjOcg0SjgIyWTzII1MGYSklWy3efGex47E9qickGZssTa-C4UTKQ8F6MU0ki3_tAH3zXx4Jka8YT3aqdXqvEhNMYWk8ZV2EwLBsVXI0VspJg1Eu3md2InK6N_5U8FEez14MmVZvp_UnF5eNdHfgIBhJfP</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1854232505</pqid></control><display><type>article</type><title>The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double‐blind, randomized trial</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><source>Wiley Online Library (Open Access Collection)</source><creator>Gomes, Aline Corado ; de Sousa, Rávila Graziany Machado ; Botelho, Patrícia Borges ; Gomes, Tatyanne Letícia Nogueira ; Prada, Patrícia Oliveira ; Mota, João Felipe</creator><creatorcontrib>Gomes, Aline Corado ; de Sousa, Rávila Graziany Machado ; Botelho, Patrícia Borges ; Gomes, Tatyanne Letícia Nogueira ; Prada, Patrícia Oliveira ; Mota, João Felipe</creatorcontrib><description>Objective To investigate whether a probiotic mix has additional effects when compared with an isolated dietary intervention on the body composition, lipid profile, endotoxemia, inflammation, and antioxidant profile. Methods Women who had excess weight or obesity were recruited to a randomized, double‐blind trial and received a probiotic mix (Lactobacillus acidophilus and casei; Lactococcus lactis; Bifidobacterium bifidum and lactis; 2 × 1010 colony‐forming units/day) (n = 21) or placebo (n = 22) for 8 weeks. Both groups received a dietary prescription. Body composition was assessed by anthropometry and dual‐energy X‐ray absorptiometry. The lipid profile, lipid accumulation product, plasma fatty acids, lipopolysaccharide, interleukin‐6, interleukin‐10, tumor necrosis factor‐α, adiponectin, and the antioxidant enzymes activities were analyzed. Results In comparison with the dietary intervention group, the dietary intervention + probiotic mix group showed a greater reduction in the waist circumference (−3.40% vs. −5.48%, P = 0.03), waist‐height ratio (−3.27% vs. −5.00%, P = 0.02), conicity index (−2.43% vs. −4.09% P = 0.03), and plasma polyunsaturated fatty acids (5.65% vs. −18.63%, P = 0.04) and an increase in the activity of glutathione peroxidase (−16.67% vs. 15.62%, P &lt; 0.01). Conclusions Supplementation of a probiotic mix reduced abdominal adiposity and increased antioxidant enzyme activity in a more effective way than an isolated dietary intervention.</description><identifier>ISSN: 1930-7381</identifier><identifier>EISSN: 1930-739X</identifier><identifier>DOI: 10.1002/oby.21671</identifier><identifier>PMID: 28008750</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adiposity - drug effects ; Adult ; Antioxidants ; Antioxidants - administration &amp; dosage ; Bacteria ; Body Mass Index ; Diet, Reducing - methods ; Disease ; Double-Blind Method ; Enzymes ; Fatty acids ; Female ; Food ; Hormone replacement therapy ; Humans ; Metabolism ; Nutrition research ; Obesity ; Obesity, Abdominal - drug therapy ; Obesity, Abdominal - prevention &amp; control ; Probiotics ; Probiotics - administration &amp; dosage ; Rodents ; Studies ; Womens health</subject><ispartof>Obesity (Silver Spring, Md.), 2017-01, Vol.25 (1), p.30-38</ispartof><rights>2016 The Obesity Society</rights><rights>2016 The Obesity Society.</rights><rights>Copyright Blackwell Publishing Ltd. Jan 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3881-6be27ecc3c25fdb80abaabf938c1a8fab06a28a11270baec024cb36f0fe091b03</citedby><cites>FETCH-LOGICAL-c3881-6be27ecc3c25fdb80abaabf938c1a8fab06a28a11270baec024cb36f0fe091b03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Foby.21671$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Foby.21671$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28008750$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gomes, Aline Corado</creatorcontrib><creatorcontrib>de Sousa, Rávila Graziany Machado</creatorcontrib><creatorcontrib>Botelho, Patrícia Borges</creatorcontrib><creatorcontrib>Gomes, Tatyanne Letícia Nogueira</creatorcontrib><creatorcontrib>Prada, Patrícia Oliveira</creatorcontrib><creatorcontrib>Mota, João Felipe</creatorcontrib><title>The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double‐blind, randomized trial</title><title>Obesity (Silver Spring, Md.)</title><addtitle>Obesity (Silver Spring)</addtitle><description>Objective To investigate whether a probiotic mix has additional effects when compared with an isolated dietary intervention on the body composition, lipid profile, endotoxemia, inflammation, and antioxidant profile. Methods Women who had excess weight or obesity were recruited to a randomized, double‐blind trial and received a probiotic mix (Lactobacillus acidophilus and casei; Lactococcus lactis; Bifidobacterium bifidum and lactis; 2 × 1010 colony‐forming units/day) (n = 21) or placebo (n = 22) for 8 weeks. Both groups received a dietary prescription. Body composition was assessed by anthropometry and dual‐energy X‐ray absorptiometry. The lipid profile, lipid accumulation product, plasma fatty acids, lipopolysaccharide, interleukin‐6, interleukin‐10, tumor necrosis factor‐α, adiponectin, and the antioxidant enzymes activities were analyzed. Results In comparison with the dietary intervention group, the dietary intervention + probiotic mix group showed a greater reduction in the waist circumference (−3.40% vs. −5.48%, P = 0.03), waist‐height ratio (−3.27% vs. −5.00%, P = 0.02), conicity index (−2.43% vs. −4.09% P = 0.03), and plasma polyunsaturated fatty acids (5.65% vs. −18.63%, P = 0.04) and an increase in the activity of glutathione peroxidase (−16.67% vs. 15.62%, P &lt; 0.01). Conclusions Supplementation of a probiotic mix reduced abdominal adiposity and increased antioxidant enzyme activity in a more effective way than an isolated dietary intervention.</description><subject>Adiposity - drug effects</subject><subject>Adult</subject><subject>Antioxidants</subject><subject>Antioxidants - administration &amp; dosage</subject><subject>Bacteria</subject><subject>Body Mass Index</subject><subject>Diet, Reducing - methods</subject><subject>Disease</subject><subject>Double-Blind Method</subject><subject>Enzymes</subject><subject>Fatty acids</subject><subject>Female</subject><subject>Food</subject><subject>Hormone replacement therapy</subject><subject>Humans</subject><subject>Metabolism</subject><subject>Nutrition research</subject><subject>Obesity</subject><subject>Obesity, Abdominal - drug therapy</subject><subject>Obesity, Abdominal - prevention &amp; control</subject><subject>Probiotics</subject><subject>Probiotics - administration &amp; dosage</subject><subject>Rodents</subject><subject>Studies</subject><subject>Womens health</subject><issn>1930-7381</issn><issn>1930-739X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10ctKxDAUBuAgiveFLyABNwrOeJJO24w7FW8guFBBV-XkhpG2GZsWHd34CD6jT2KcqgvBRThZfOeHw0_IBoMhA-B7Xk6HnGU5myPLbJzAIE_Gt_O_f8GWyEoIDwCjDFK2SJa4ABB5Csvk9freUNTatc7XWFJjrVFtoN5SpJPGS-dbp2jlnqmvKUrtK_flULuJD66dUqx1fHH92ek46VWLbRf26QHVvpOl-Xh7l6Wr9S5tIo3rL0bTtnFYrpEFi2Uw699zldycHF8fnQ0uLk_Pjw4uBioRgg0yaXhulEoUT62WAlAiSjtOhGIoLErIkAtkjOcg0SjgIyWTzII1MGYSklWy3efGex47E9qickGZssTa-C4UTKQ8F6MU0ki3_tAH3zXx4Jka8YT3aqdXqvEhNMYWk8ZV2EwLBsVXI0VspJg1Eu3md2InK6N_5U8FEez14MmVZvp_UnF5eNdHfgIBhJfP</recordid><startdate>201701</startdate><enddate>201701</enddate><creator>Gomes, Aline Corado</creator><creator>de Sousa, Rávila Graziany Machado</creator><creator>Botelho, Patrícia Borges</creator><creator>Gomes, Tatyanne Letícia Nogueira</creator><creator>Prada, Patrícia Oliveira</creator><creator>Mota, João Felipe</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201701</creationdate><title>The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double‐blind, randomized trial</title><author>Gomes, Aline Corado ; de Sousa, Rávila Graziany Machado ; Botelho, Patrícia Borges ; Gomes, Tatyanne Letícia Nogueira ; Prada, Patrícia Oliveira ; Mota, João Felipe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3881-6be27ecc3c25fdb80abaabf938c1a8fab06a28a11270baec024cb36f0fe091b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adiposity - drug effects</topic><topic>Adult</topic><topic>Antioxidants</topic><topic>Antioxidants - administration &amp; dosage</topic><topic>Bacteria</topic><topic>Body Mass Index</topic><topic>Diet, Reducing - methods</topic><topic>Disease</topic><topic>Double-Blind Method</topic><topic>Enzymes</topic><topic>Fatty acids</topic><topic>Female</topic><topic>Food</topic><topic>Hormone replacement therapy</topic><topic>Humans</topic><topic>Metabolism</topic><topic>Nutrition research</topic><topic>Obesity</topic><topic>Obesity, Abdominal - drug therapy</topic><topic>Obesity, Abdominal - prevention &amp; control</topic><topic>Probiotics</topic><topic>Probiotics - administration &amp; dosage</topic><topic>Rodents</topic><topic>Studies</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gomes, Aline Corado</creatorcontrib><creatorcontrib>de Sousa, Rávila Graziany Machado</creatorcontrib><creatorcontrib>Botelho, Patrícia Borges</creatorcontrib><creatorcontrib>Gomes, Tatyanne Letícia Nogueira</creatorcontrib><creatorcontrib>Prada, Patrícia Oliveira</creatorcontrib><creatorcontrib>Mota, João Felipe</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Obesity (Silver Spring, Md.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gomes, Aline Corado</au><au>de Sousa, Rávila Graziany Machado</au><au>Botelho, Patrícia Borges</au><au>Gomes, Tatyanne Letícia Nogueira</au><au>Prada, Patrícia Oliveira</au><au>Mota, João Felipe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double‐blind, randomized trial</atitle><jtitle>Obesity (Silver Spring, Md.)</jtitle><addtitle>Obesity (Silver Spring)</addtitle><date>2017-01</date><risdate>2017</risdate><volume>25</volume><issue>1</issue><spage>30</spage><epage>38</epage><pages>30-38</pages><issn>1930-7381</issn><eissn>1930-739X</eissn><abstract>Objective To investigate whether a probiotic mix has additional effects when compared with an isolated dietary intervention on the body composition, lipid profile, endotoxemia, inflammation, and antioxidant profile. Methods Women who had excess weight or obesity were recruited to a randomized, double‐blind trial and received a probiotic mix (Lactobacillus acidophilus and casei; Lactococcus lactis; Bifidobacterium bifidum and lactis; 2 × 1010 colony‐forming units/day) (n = 21) or placebo (n = 22) for 8 weeks. Both groups received a dietary prescription. Body composition was assessed by anthropometry and dual‐energy X‐ray absorptiometry. The lipid profile, lipid accumulation product, plasma fatty acids, lipopolysaccharide, interleukin‐6, interleukin‐10, tumor necrosis factor‐α, adiponectin, and the antioxidant enzymes activities were analyzed. Results In comparison with the dietary intervention group, the dietary intervention + probiotic mix group showed a greater reduction in the waist circumference (−3.40% vs. −5.48%, P = 0.03), waist‐height ratio (−3.27% vs. −5.00%, P = 0.02), conicity index (−2.43% vs. −4.09% P = 0.03), and plasma polyunsaturated fatty acids (5.65% vs. −18.63%, P = 0.04) and an increase in the activity of glutathione peroxidase (−16.67% vs. 15.62%, P &lt; 0.01). Conclusions Supplementation of a probiotic mix reduced abdominal adiposity and increased antioxidant enzyme activity in a more effective way than an isolated dietary intervention.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>28008750</pmid><doi>10.1002/oby.21671</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1930-7381
ispartof Obesity (Silver Spring, Md.), 2017-01, Vol.25 (1), p.30-38
issn 1930-7381
1930-739X
language eng
recordid cdi_proquest_miscellaneous_1852784505
source MEDLINE; Access via Wiley Online Library; Wiley Online Library (Open Access Collection)
subjects Adiposity - drug effects
Adult
Antioxidants
Antioxidants - administration & dosage
Bacteria
Body Mass Index
Diet, Reducing - methods
Disease
Double-Blind Method
Enzymes
Fatty acids
Female
Food
Hormone replacement therapy
Humans
Metabolism
Nutrition research
Obesity
Obesity, Abdominal - drug therapy
Obesity, Abdominal - prevention & control
Probiotics
Probiotics - administration & dosage
Rodents
Studies
Womens health
title The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double‐blind, randomized trial
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T12%3A21%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20additional%20effects%20of%20a%20probiotic%20mix%20on%20abdominal%20adiposity%20and%20antioxidant%20Status:%20A%20double%E2%80%90blind,%20randomized%20trial&rft.jtitle=Obesity%20(Silver%20Spring,%20Md.)&rft.au=Gomes,%20Aline%20Corado&rft.date=2017-01&rft.volume=25&rft.issue=1&rft.spage=30&rft.epage=38&rft.pages=30-38&rft.issn=1930-7381&rft.eissn=1930-739X&rft_id=info:doi/10.1002/oby.21671&rft_dat=%3Cproquest_cross%3E1852784505%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1854232505&rft_id=info:pmid/28008750&rfr_iscdi=true