Division modes and physical asymmetry in cerebral cortex progenitors
Highlights • Temporal gene progression in cortical precursors is independent of cell division. • Translocating division mode drives germinal zone evolution in the cerebral cortex. • Apico-basal positioning of apical progenitor daughter cells: neurons are born apically. • Asymmetry in cytoplasmic com...
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| Veröffentlicht in: | Current opinion in neurobiology 2017-02, Vol.42, p.75-83 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Highlights • Temporal gene progression in cortical precursors is independent of cell division. • Translocating division mode drives germinal zone evolution in the cerebral cortex. • Apico-basal positioning of apical progenitor daughter cells: neurons are born apically. • Asymmetry in cytoplasmic components during AP division, effect on cell fate. |
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| ISSN: | 0959-4388 1873-6882 |
| DOI: | 10.1016/j.conb.2016.11.009 |