Increased incidence of clinical hypotension with etomidate compared to ketamine for intubation in septic patients: a propensity matched analysis

Abstract Purpose This study compared the incidence of clinical hypotension between ketamine and etomidate within a 24 hour (hr) period following endotracheal intubation. Materials and methods This single-center, retrospective propensity-matched cohort study included septic patients admitted to our medical intensive care unit who received either etomidate or ketamine for intubation. Clinical hypotension was defined as any one of the following: mean arterial pressure (MAP) decrease >40% compared to baseline and MAP