Aortic root surgery with circulatory arrest: Predictors of prolonged postoperative hospital stay

Abstract Objective Little is known about the outcomes of aortic root operations that involve inducing hypothermic circulatory arrest for relatively extensive proximal aortic surgery. We attempted to identify predictors of postoperative hospital length of stay (LOS) and factors that affect postoperat...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2017-03, Vol.153 (3), p.511-518
Hauptverfasser: Preventza, Ourania, MD, Coselli, Joseph S., MD, Garcia, Andrea, MD, Akvan, Shahab, MD, Kashyap, Sarang, MD, Simpson, Katherine H., MS, Price, Matt D., MD, de la Cruz, Kim I., MD, Spiliotopoulos, Konstantinos, MD, PhD, FETCS, Cornwell, Lorraine D., MD, Bakaeen, Faisal G., MD, Omer, Shuab, MD, Cooley, Denton A., MD
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Sprache:eng
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Zusammenfassung:Abstract Objective Little is known about the outcomes of aortic root operations that involve inducing hypothermic circulatory arrest for relatively extensive proximal aortic surgery. We attempted to identify predictors of postoperative hospital length of stay (LOS) and factors that affect postoperative recovery. Methods During 2006-2014, 247 of 265 patients (93.2%) with disease extending into the aortic arch survived aortic root operations (206 elective, 41 urgent/emergent) in which hypothermic circulatory arrest with moderate hypothermia was used. Stepwise multivariate regression analysis was performed to identify predictors of LOS (as a continuous variable) and prolonged LOS (defined as LOS >9 days, the median for the cohort). By this definition, 111 patients (45%) had prolonged LOS and 136 (55%) did not. Results Preoperative factors that independently predicted longer LOS in the entire cohort included age ( P  = .0014), redo sternotomy ( P  = .0047), and intraoperative packed red blood cell (PRBC) transfusion ( P  = .0007). Redo sternotomy and intraoperative PRBC transfusion also predicted longer LOS in 3 subgroup analyses: one of elective cases, one from which total arch replacement procedures were excluded, and one limited to patients who were discharged home. Age predicted longer LOS in the non-total arch (hemiarch) replacement patients. Ventilator support >48 hours ( P  
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2016.10.090