Toxoplasmosis versus lymphoma: Cerebral lesion characterization using DSC-MRI revisited

Highlights • Contemporary DSC methodology should be used to establish rCBV thresholds. • Proper data reduction approaches best evaluate rCBV-based disease status. • A rCBV threshold of 1.5 best distinguishes toxoplasmosis from lymphoma.

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Veröffentlicht in:Clinical neurology and neurosurgery 2017-01, Vol.152, p.84-89
Hauptverfasser: Dibble, Elizabeth H, Boxerman, Jerrold L, Baird, Grayson L, Donahue, John E, Rogg, Jeffrey M
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container_start_page 84
container_title Clinical neurology and neurosurgery
container_volume 152
creator Dibble, Elizabeth H
Boxerman, Jerrold L
Baird, Grayson L
Donahue, John E
Rogg, Jeffrey M
description Highlights • Contemporary DSC methodology should be used to establish rCBV thresholds. • Proper data reduction approaches best evaluate rCBV-based disease status. • A rCBV threshold of 1.5 best distinguishes toxoplasmosis from lymphoma.
doi_str_mv 10.1016/j.clineuro.2016.11.023
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subjects Abscesses
Acquired immune deficiency syndrome
Adult
Age
Aged
Aged, 80 and over
AIDS
B-cell lymphoma
Biometrics
Biopsy
Blood
Blood volume
Brain
Brain Neoplasms - diagnostic imaging
Brain tumors
Central nervous system
Cerebral blood flow
Cerebrovascular Circulation - physiology
Complications
Computer programs
Diagnosis, Differential
Diffusion coefficient
DSC-MRI
Extravasation
Female
Gadolinium
Glioma
Guidelines
Hemorrhage
Highly active antiretroviral therapy
Histopathology
HIV
Human immunodeficiency virus
Humans
Immune status
Infections
Lesions
Longitudinal studies
Lymphocytes B
Lymphoma
Lymphoma - diagnostic imaging
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Medical wastes
Methods
Middle Aged
Nervous system
Neuroimaging
Neurological complications
Neurology
Neurosurgery
NMR
Nuclear magnetic resonance
Pathology
Radiology
rCBV
Research design
Resonance
Retrospective Studies
Segmentation
Spectroscopy
Spectrum analysis
Substantia alba
Time series
Toxoplasmosis
Toxoplasmosis, Cerebral - diagnostic imaging
title Toxoplasmosis versus lymphoma: Cerebral lesion characterization using DSC-MRI revisited
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