Toxoplasmosis versus lymphoma: Cerebral lesion characterization using DSC-MRI revisited

Highlights • Contemporary DSC methodology should be used to establish rCBV thresholds. • Proper data reduction approaches best evaluate rCBV-based disease status. • A rCBV threshold of 1.5 best distinguishes toxoplasmosis from lymphoma.

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Bibliographische Detailangaben
Veröffentlicht in:	Clinical neurology and neurosurgery 2017-01, Vol.152, p.84-89
Hauptverfasser:	Dibble, Elizabeth H, Boxerman, Jerrold L, Baird, Grayson L, Donahue, John E, Rogg, Jeffrey M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abscesses Acquired immune deficiency syndrome Adult Age Aged Aged, 80 and over AIDS B-cell lymphoma Biometrics Biopsy Blood Blood volume Brain Brain Neoplasms - diagnostic imaging Brain tumors Central nervous system Cerebral blood flow Cerebrovascular Circulation - physiology Complications Computer programs Diagnosis, Differential Diffusion coefficient DSC-MRI Extravasation Female Gadolinium Glioma Guidelines Hemorrhage Highly active antiretroviral therapy Histopathology HIV Human immunodeficiency virus Humans Immune status Infections Lesions Longitudinal studies Lymphocytes B Lymphoma Lymphoma - diagnostic imaging Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medical wastes Methods Middle Aged Nervous system Neuroimaging Neurological complications Neurology Neurosurgery NMR Nuclear magnetic resonance Pathology Radiology rCBV Research design Resonance Retrospective Studies Segmentation Spectroscopy Spectrum analysis Substantia alba Time series Toxoplasmosis Toxoplasmosis, Cerebral - diagnostic imaging
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Beschreibung
Zusammenfassung:	Highlights • Contemporary DSC methodology should be used to establish rCBV thresholds. • Proper data reduction approaches best evaluate rCBV-based disease status. • A rCBV threshold of 1.5 best distinguishes toxoplasmosis from lymphoma.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2016.11.023