An elevated pro-inflammatory cytokines profile in Behcet’s disease: A multiplex analysis

An elevated pro-inflammatory cytokines profile in Behcet’s disease: A multiplex analysis

Highlights • Levels of innate immunity-related cytokines are increased in BD patients. • Th1- and Th17-related cytokines were significantly higher in BD patients. • Disease activity score and clinical activity index are affected by the levels IL-6.

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Bibliographische Detailangaben
Veröffentlicht in:Immunology letters 2017-06, Vol.186, p.46-51
Hauptverfasser: Gholijani, Nasser, Ataollahi, Mohammad Reza, Samiei, Afshin, Aflaki, Elham, Shenavandeh, Saeedeh, EskandarKamali-Sarvestani
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Allergy and Immunology
Behcet Syndrome - immunology
Behcet’s disease
Cytokine profiles
Cytokines - blood
Cytokines - genetics
Disease Progression
Female
Gene Expression Profiling
Humans
Immunity, Innate
Inflammation Mediators - blood
Innate immunity
Male
Middle Aged
Protein Array Analysis
Severity of Illness Index
Th1
Th1 Cells - immunology
Th17
Th17 Cells - immunology
Th2
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Beschreibung
Zusammenfassung:Highlights • Levels of innate immunity-related cytokines are increased in BD patients. • Th1- and Th17-related cytokines were significantly higher in BD patients. • Disease activity score and clinical activity index are affected by the levels IL-6.
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2016.12.001