Human brain responses to gastrointestinal nutrients and gut hormones

Human brain responses to gastrointestinal nutrients and gut hormones

Highlights • Advances in functional imaging have provided new insights into human brain responses. • Response matrices can be mapped in the brain, and differ between nutrient classes. • Gut hormones including CCK, GLP-1, PYY and ghrelin affect brain responses. • Interactions between homeostatic regi...

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Veröffentlicht in:Current opinion in pharmacology 2016-12, Vol.31, p.8-12
Hauptverfasser: McLaughlin, John T, McKie, Shane
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Brain - metabolism
Brain Mapping
Eating - physiology
Feeding and Eating Disorders - physiopathology
Food
Gastrointestinal Hormones - metabolism
Homeostasis
Humans
Internal Medicine
Medical Education
Obesity - physiopathology
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Beschreibung
Zusammenfassung:Highlights • Advances in functional imaging have provided new insights into human brain responses. • Response matrices can be mapped in the brain, and differ between nutrient classes. • Gut hormones including CCK, GLP-1, PYY and ghrelin affect brain responses. • Interactions between homeostatic regions and higher centre responses can be studied. • Gut endocrine status (fasted or fed) strongly influences responses to food images.
ISSN:1471-4892
1471-4973
DOI:10.1016/j.coph.2016.08.006