Effects of deep brain stimulation of the subthalamic nucleus on perceptual decision making

Effects of deep brain stimulation of the subthalamic nucleus on perceptual decision making

Highlights • STN-DBS in PD modulates perceptual decision-making. • STN-DBS effects are inter-individually variable and depend on baseline cognitive abilities of the PD patients. • Pre-OP evaluation of individual impulsivity might be able to reduce the risk of STN-DBS induced impulse control disorder...

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Veröffentlicht in:Neuroscience 2017-02, Vol.343, p.140-146
Hauptverfasser: Zaehle, Tino, Wagenbreth, Caroline, Voges, Jürgen, Heinze, Hans-Jochen, Galazki, Imke
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Analysis of Variance
Cognition - physiology
DBS
decision making
Decision Making - physiology
Deep Brain Stimulation - methods
Deep Brain Stimulation - psychology
Female
Humans
Impulsive Behavior - physiology
Male
Middle Aged
Neurology
Neuropsychological Tests
Parkinson Disease - physiopathology
Parkinson Disease - psychology
Parkinson Disease - therapy
STN
Subthalamic Nucleus - physiopathology
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Beschreibung
Zusammenfassung:Highlights • STN-DBS in PD modulates perceptual decision-making. • STN-DBS effects are inter-individually variable and depend on baseline cognitive abilities of the PD patients. • Pre-OP evaluation of individual impulsivity might be able to reduce the risk of STN-DBS induced impulse control disorders.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2016.11.044