Determination of the minimal erythema dose for ultraviolet A1 radiation

Summary Background There is limited knowledge of the potential of ultraviolet A1 (UVA1) radiation to induce erythema. Objectives To investigate the minimal erythema dose (MED) for UVA1 in a German and Austrian population and to determine UVA1 dose–response curves for erythema and pigmentation. Metho...

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Veröffentlicht in:British journal of dermatology (1951) 2017-07, Vol.177 (1), p.238-244
Hauptverfasser: Gambichler, T., Majert, J., Pljakic, A., Rooms, I., Wolf, P.
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Sprache:eng
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Zusammenfassung:Summary Background There is limited knowledge of the potential of ultraviolet A1 (UVA1) radiation to induce erythema. Objectives To investigate the minimal erythema dose (MED) for UVA1 in a German and Austrian population and to determine UVA1 dose–response curves for erythema and pigmentation. Methods We determined the UVA1‐MED in 59 participants using a geometric increase in the dose. Visual readings of erythema and pigmentation were performed at 10 min, 2 h and 24 h after the UVA1 irradiation. Colorimetric measurements were taken to determine erythema (a* value) and pigmentation (L* value) objectively. Results More than 30% (18 of 59) of the participants had a high‐dose UVA1‐MED (> 70–130 J cm−2); 56% (33) had no detectable UVA1‐MED after 24 h and eight (14%) had a medium‐dose UVA1‐MED (20–70 J cm−2). We observed a stepwise decrease of the a* value measured at the UVA1‐MED skin site from 10 min to 2 h and 24 h (P 
ISSN:0007-0963
1365-2133
DOI:10.1111/bjd.15245