Pharmaceutical aerosols deposition patterns from a Dry Powder Inhaler: Euler Lagrangian prediction and validation
Highlights • Elimination of the MouthPiece device and use a conical spray framework for the modelling. • CFD predicted a higher deposition on the rings (Zygote model) due to higher vorticity generation. • CFD predicted a higher deposition on the Zygote model, due to the slanting geometry. • Enhanced...
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| Veröffentlicht in: | Medical engineering & physics 2017-04, Vol.42, p.35-47 |
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| container_title | Medical engineering & physics |
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| creator | (Ravi) Kannan, Ravishekar Przekwas, A.J Singh, Narender Delvadia, Renishkumar Tian, Geng Walenga, Ross |
| description | Highlights • Elimination of the MouthPiece device and use a conical spray framework for the modelling. • CFD predicted a higher deposition on the rings (Zygote model) due to higher vorticity generation. • CFD predicted a higher deposition on the Zygote model, due to the slanting geometry. • Enhanced deposition in the 1st generation region due to the presence of the rings. • CFD predicted recirculation of lighter particles below the construction region (Zygote model). |
| doi_str_mv | 10.1016/j.medengphy.2016.11.007 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1350-4533 |
| ispartof | Medical engineering & physics, 2017-04, Vol.42, p.35-47 |
| issn | 1350-4533 1873-4030 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Aerosols Cartilaginous rings Computational fluid dynamics Computer Simulation Deposition Dry Powder Inhalers Hydrodynamics Novolizer Pharmaceutical Preparations - administration & dosage Radiology Reproducibility of Results Vorticity |
| title | Pharmaceutical aerosols deposition patterns from a Dry Powder Inhaler: Euler Lagrangian prediction and validation |
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