Pharmaceutical aerosols deposition patterns from a Dry Powder Inhaler: Euler Lagrangian prediction and validation

Highlights • Elimination of the MouthPiece device and use a conical spray framework for the modelling. • CFD predicted a higher deposition on the rings (Zygote model) due to higher vorticity generation. • CFD predicted a higher deposition on the Zygote model, due to the slanting geometry. • Enhanced deposition in the 1st generation region due to the presence of the rings. • CFD predicted recirculation of lighter particles below the construction region (Zygote model).