Prolactin and cortisol regulate branchial claudin expression in Japanese medaka

Prolactin and cortisol regulate branchial claudin expression in Japanese medaka

Highlights • Cortisol up-regulated gill cftr, ncc2b, cldn10 paralogs , cldn27a and cldn30c, • Prolactin decreases cftr and increases ncc2b in a concentration-dependent manner, • Prolactin up-regulates cldn10c , cldn10f and cldn28b, • Both hormones directly modulate determinants of gill paracellular...

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Veröffentlicht in:General and comparative endocrinology 2017-01, Vol.240, p.77-83
Hauptverfasser: Bossus, Maryline C, Bollinger, Rebecca J, Justin Reed, P, Tipsmark, Christian K
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Claudins - metabolism
Endocrinology & Metabolism
Euryhaline teleost
Freshwater
Gills - metabolism
Hormonal regulation
Hydrocortisone - metabolism
In vitro
Japan
Oryzias
Oryzias latipes
Osmoregulation
Paracellular ion transport
Prolactin - metabolism
Tight junctions
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Beschreibung
Zusammenfassung:Highlights • Cortisol up-regulated gill cftr, ncc2b, cldn10 paralogs , cldn27a and cldn30c, • Prolactin decreases cftr and increases ncc2b in a concentration-dependent manner, • Prolactin up-regulates cldn10c , cldn10f and cldn28b, • Both hormones directly modulate determinants of gill paracellular transport.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2016.09.010