Four-dimensional hysterosalpingo-contrast sonography with auxiliary hydrogen peroxide examination for the diagnosis of fallopian tube patency following interventional treatment of ovarian ectopic cysts

Objective The present study aimed to explore the practical value of using four-dimensional hysterosalpingo-contrast sonography with auxiliary hydrogen peroxide examination which is necessary for the diagnosis of fallopian tube patency following treatment of ovarian ectopic cysts. Methods A retrospective analysis of hysterosalpingography (HSG) examination data from 71 patients who had received sonography-guided interventional treatment for ovarian ectopic cysts at the Fourth Affiliated Hospital of Harbin Medical University was carried out. The 71 cases were divided into three groups. Four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy) with the contrast agent SonoVue was carried out in the first group (4D-HyCoSy group), hydrogen peroxide (H 2 O 2 ) examinations were carried out in the second group (H 2 O 2 group), and the final group consisted of patients who underwent 4D-HyCoSy followed by an auxiliary H 2 O 2 examination where necessary (4D-HyCoSy/H 2 O 2 group). Results of these examinations were then compared to those of a standard HSG examination using lipiodol radiography that had been carried out a month beforehand. Results (1) The rates of diagnostic accordance with standard HSG examination results for the 4D-HyCoSy, H 2 O 2 , and 4D-HyCoSy/H 2 O 2 groups were 86.9, 70.5 and 91.8% respectively. The H 2 O 2 group accordance rate was significantly lower than that of the other two groups ( p