Pulmonary vein reconnection following catheter ablation of atrial fibrillation using the second-generation cryoballoon versus open-irrigated radiofrequency: results of a multicenter analysis
Purpose Catheter ablation of atrial fibrillation (CAAF) using the cryoballoon has emerged as an alternate strategy to point-by-point radiofrequency. However, there is little comparative data on long-term durability of pulmonary vein (PV) isolation comparing these two modalities. Methods In this mult...
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Veröffentlicht in: | Journal of interventional cardiac electrophysiology 2016-12, Vol.47 (3), p.341-348 |
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creator | Aryana, Arash Singh, Sheldon M. Mugnai, Giacomo de Asmundis, Carlo Kowalski, Marcin Pujara, Deep K. Cohen, Andrew I. Singh, Steve K. Fuenzalida, Charles E. Prager, Nelson Bowers, Mark R. O’Neill, Padraig Gearoid Brugada, Pedro d’Avila, André Chierchia, Gian-Battista |
description | Purpose
Catheter ablation of atrial fibrillation (CAAF) using the cryoballoon has emerged as an alternate strategy to point-by-point radiofrequency. However, there is little comparative data on long-term durability of pulmonary vein (PV) isolation comparing these two modalities.
Methods
In this multicenter, retrospective analysis, the incidences/patterns of late PV reconnection following an index CAAF using the second-generation cryoballoon versus open-irrigated, non-force-sensing radiofrequency were examined.
Results
Of the 2002 patients who underwent a first-time CAAF, 186/1126 patients (16.5 %) ablated using cryoballoon and 174/876 patients (19.9 %) with non-contact force-guided radiofrequency required a repeat procedure at 11 ± 5 months. During follow-up, the incidence of atrial flutters/tachycardias was lower (19.9 vs. 32.8 %;
p
= 0.005) and fewer patients exhibited PV reconnection (47.3 vs. 60.9 %;
p
= 0.007) with cryoballoon versus radiofrequency. Additionally, fewer PVs had reconnected with cryoballoon versus radiofrequency (18.8 vs. 34.6 %;
p
|
doi_str_mv | 10.1007/s10840-016-0172-z |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1846416918</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4250355041</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-e072d920476ab43db4462096dc82b1da48e799b838d1a9d2c647e6672e89311e3</originalsourceid><addsrcrecordid>eNqNkl2L1TAQhoso7rr6A7yRgDfeVJM0zYd3svgFC3qh4F1Jk-kxS5sck3bl7I_ztzk9PYoIghchQ-bJOzPMW1WPGX3OKFUvCqNa0JoyiUfx-vZOdc5aDHRr2rsYN7qptWq_nFUPSrmmlBrK5f3qjCuhWiPMefXj4zJOKdp8IDcQIsngUozg5pAiGdI4pu8h7oiz81eYIRPbj_aYSwOxcw52JEPocxhPz0tZcYRJWZV8vYMIecu5fEi9RUmMbyCXpZC0h1iHnMPOzuBJtj6kIcO3BaI7vMRuyjLO5ViMTBgGB_HYRrTjoYTysLo32LHAo9N9UX1-8_rT5bv66sPb95evrmonFJtroIp7w6lQ0vai8b0QklMjvdO8Z94KDcqYXjfaM2s8d1IokFJx0KZhDJqL6tmmu88JmytzN4XiAKeOkJbSMS2kYNIw_R8olwoXIziiT_9Cr9OScbSVakwrdUslUmyjXE6lZBi6fQ4TbqxjtFt90G0-6NAH3eqD7hb_PDkpL_0E_vePX4tHgG9AwVTcQf6j9D9VfwJu5MN6</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1839568506</pqid></control><display><type>article</type><title>Pulmonary vein reconnection following catheter ablation of atrial fibrillation using the second-generation cryoballoon versus open-irrigated radiofrequency: results of a multicenter analysis</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Aryana, Arash ; Singh, Sheldon M. ; Mugnai, Giacomo ; de Asmundis, Carlo ; Kowalski, Marcin ; Pujara, Deep K. ; Cohen, Andrew I. ; Singh, Steve K. ; Fuenzalida, Charles E. ; Prager, Nelson ; Bowers, Mark R. ; O’Neill, Padraig Gearoid ; Brugada, Pedro ; d’Avila, André ; Chierchia, Gian-Battista</creator><creatorcontrib>Aryana, Arash ; Singh, Sheldon M. ; Mugnai, Giacomo ; de Asmundis, Carlo ; Kowalski, Marcin ; Pujara, Deep K. ; Cohen, Andrew I. ; Singh, Steve K. ; Fuenzalida, Charles E. ; Prager, Nelson ; Bowers, Mark R. ; O’Neill, Padraig Gearoid ; Brugada, Pedro ; d’Avila, André ; Chierchia, Gian-Battista</creatorcontrib><description>Purpose
Catheter ablation of atrial fibrillation (CAAF) using the cryoballoon has emerged as an alternate strategy to point-by-point radiofrequency. However, there is little comparative data on long-term durability of pulmonary vein (PV) isolation comparing these two modalities.
Methods
In this multicenter, retrospective analysis, the incidences/patterns of late PV reconnection following an index CAAF using the second-generation cryoballoon versus open-irrigated, non-force-sensing radiofrequency were examined.
Results
Of the 2002 patients who underwent a first-time CAAF, 186/1126 patients (16.5 %) ablated using cryoballoon and 174/876 patients (19.9 %) with non-contact force-guided radiofrequency required a repeat procedure at 11 ± 5 months. During follow-up, the incidence of atrial flutters/tachycardias was lower (19.9 vs. 32.8 %;
p
= 0.005) and fewer patients exhibited PV reconnection (47.3 vs. 60.9 %;
p
= 0.007) with cryoballoon versus radiofrequency. Additionally, fewer PVs had reconnected with cryoballoon versus radiofrequency (18.8 vs. 34.6 %;
p
< 0.001). With cryoballoon, the right inferior (
p
< 0.001) and left common (
p
= 0.039) PVs were more likely to exhibit late reconnection, versus the left superior PV with radiofrequency (
p
= 0.012). However, when comparing the two strategies, the left common PV was more likely to exhibit reconnection with cryoballoon, whereas all other PVs with the exception of the right inferior PV demonstrated a lower reconnection rate with cryoballoon versus radiofrequency. Lastly, in a logistic regression multivariate analysis, cryoballoon ablation and PV ablation time emerged as significant predictors of durable PV isolation at repeat procedure.
Conclusions
In this large multicenter, retrospective analysis, CAAF using the second-generation cryoballoon was associated with improved durability of PV isolation compared to open-irrigated, non-force-sensing radiofrequency.</description><identifier>ISSN: 1383-875X</identifier><identifier>EISSN: 1572-8595</identifier><identifier>DOI: 10.1007/s10840-016-0172-z</identifier><identifier>PMID: 27475949</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Atrial Fibrillation - diagnosis ; Atrial Fibrillation - epidemiology ; Atrial Fibrillation - surgery ; Cardiology ; Catheter Ablation - instrumentation ; Catheter Ablation - utilization ; Cryosurgery - instrumentation ; Cryosurgery - utilization ; Equipment Design ; Equipment Failure Analysis ; Female ; Heart Conduction System - surgery ; Humans ; Incidence ; Internationality ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Operative Time ; Prevalence ; Pulmonary Veins - surgery ; Recurrence ; Risk Factors ; Therapeutic Irrigation - utilization ; Treatment Failure ; Treatment Outcome</subject><ispartof>Journal of interventional cardiac electrophysiology, 2016-12, Vol.47 (3), p.341-348</ispartof><rights>Springer Science+Business Media New York 2016</rights><rights>Journal of Interventional Cardiac Electrophysiology is a copyright of Springer, 2016.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-e072d920476ab43db4462096dc82b1da48e799b838d1a9d2c647e6672e89311e3</citedby><cites>FETCH-LOGICAL-c471t-e072d920476ab43db4462096dc82b1da48e799b838d1a9d2c647e6672e89311e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10840-016-0172-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10840-016-0172-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27475949$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aryana, Arash</creatorcontrib><creatorcontrib>Singh, Sheldon M.</creatorcontrib><creatorcontrib>Mugnai, Giacomo</creatorcontrib><creatorcontrib>de Asmundis, Carlo</creatorcontrib><creatorcontrib>Kowalski, Marcin</creatorcontrib><creatorcontrib>Pujara, Deep K.</creatorcontrib><creatorcontrib>Cohen, Andrew I.</creatorcontrib><creatorcontrib>Singh, Steve K.</creatorcontrib><creatorcontrib>Fuenzalida, Charles E.</creatorcontrib><creatorcontrib>Prager, Nelson</creatorcontrib><creatorcontrib>Bowers, Mark R.</creatorcontrib><creatorcontrib>O’Neill, Padraig Gearoid</creatorcontrib><creatorcontrib>Brugada, Pedro</creatorcontrib><creatorcontrib>d’Avila, André</creatorcontrib><creatorcontrib>Chierchia, Gian-Battista</creatorcontrib><title>Pulmonary vein reconnection following catheter ablation of atrial fibrillation using the second-generation cryoballoon versus open-irrigated radiofrequency: results of a multicenter analysis</title><title>Journal of interventional cardiac electrophysiology</title><addtitle>J Interv Card Electrophysiol</addtitle><addtitle>J Interv Card Electrophysiol</addtitle><description>Purpose
Catheter ablation of atrial fibrillation (CAAF) using the cryoballoon has emerged as an alternate strategy to point-by-point radiofrequency. However, there is little comparative data on long-term durability of pulmonary vein (PV) isolation comparing these two modalities.
Methods
In this multicenter, retrospective analysis, the incidences/patterns of late PV reconnection following an index CAAF using the second-generation cryoballoon versus open-irrigated, non-force-sensing radiofrequency were examined.
Results
Of the 2002 patients who underwent a first-time CAAF, 186/1126 patients (16.5 %) ablated using cryoballoon and 174/876 patients (19.9 %) with non-contact force-guided radiofrequency required a repeat procedure at 11 ± 5 months. During follow-up, the incidence of atrial flutters/tachycardias was lower (19.9 vs. 32.8 %;
p
= 0.005) and fewer patients exhibited PV reconnection (47.3 vs. 60.9 %;
p
= 0.007) with cryoballoon versus radiofrequency. Additionally, fewer PVs had reconnected with cryoballoon versus radiofrequency (18.8 vs. 34.6 %;
p
< 0.001). With cryoballoon, the right inferior (
p
< 0.001) and left common (
p
= 0.039) PVs were more likely to exhibit late reconnection, versus the left superior PV with radiofrequency (
p
= 0.012). However, when comparing the two strategies, the left common PV was more likely to exhibit reconnection with cryoballoon, whereas all other PVs with the exception of the right inferior PV demonstrated a lower reconnection rate with cryoballoon versus radiofrequency. Lastly, in a logistic regression multivariate analysis, cryoballoon ablation and PV ablation time emerged as significant predictors of durable PV isolation at repeat procedure.
Conclusions
In this large multicenter, retrospective analysis, CAAF using the second-generation cryoballoon was associated with improved durability of PV isolation compared to open-irrigated, non-force-sensing radiofrequency.</description><subject>Atrial Fibrillation - diagnosis</subject><subject>Atrial Fibrillation - epidemiology</subject><subject>Atrial Fibrillation - surgery</subject><subject>Cardiology</subject><subject>Catheter Ablation - instrumentation</subject><subject>Catheter Ablation - utilization</subject><subject>Cryosurgery - instrumentation</subject><subject>Cryosurgery - utilization</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Female</subject><subject>Heart Conduction System - surgery</subject><subject>Humans</subject><subject>Incidence</subject><subject>Internationality</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Operative Time</subject><subject>Prevalence</subject><subject>Pulmonary Veins - surgery</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Therapeutic Irrigation - utilization</subject><subject>Treatment Failure</subject><subject>Treatment Outcome</subject><issn>1383-875X</issn><issn>1572-8595</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkl2L1TAQhoso7rr6A7yRgDfeVJM0zYd3svgFC3qh4F1Jk-kxS5sck3bl7I_ztzk9PYoIghchQ-bJOzPMW1WPGX3OKFUvCqNa0JoyiUfx-vZOdc5aDHRr2rsYN7qptWq_nFUPSrmmlBrK5f3qjCuhWiPMefXj4zJOKdp8IDcQIsngUozg5pAiGdI4pu8h7oiz81eYIRPbj_aYSwOxcw52JEPocxhPz0tZcYRJWZV8vYMIecu5fEi9RUmMbyCXpZC0h1iHnMPOzuBJtj6kIcO3BaI7vMRuyjLO5ViMTBgGB_HYRrTjoYTysLo32LHAo9N9UX1-8_rT5bv66sPb95evrmonFJtroIp7w6lQ0vai8b0QklMjvdO8Z94KDcqYXjfaM2s8d1IokFJx0KZhDJqL6tmmu88JmytzN4XiAKeOkJbSMS2kYNIw_R8olwoXIziiT_9Cr9OScbSVakwrdUslUmyjXE6lZBi6fQ4TbqxjtFt90G0-6NAH3eqD7hb_PDkpL_0E_vePX4tHgG9AwVTcQf6j9D9VfwJu5MN6</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>Aryana, Arash</creator><creator>Singh, Sheldon M.</creator><creator>Mugnai, Giacomo</creator><creator>de Asmundis, Carlo</creator><creator>Kowalski, Marcin</creator><creator>Pujara, Deep K.</creator><creator>Cohen, Andrew I.</creator><creator>Singh, Steve K.</creator><creator>Fuenzalida, Charles E.</creator><creator>Prager, Nelson</creator><creator>Bowers, Mark R.</creator><creator>O’Neill, Padraig Gearoid</creator><creator>Brugada, Pedro</creator><creator>d’Avila, André</creator><creator>Chierchia, Gian-Battista</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20161201</creationdate><title>Pulmonary vein reconnection following catheter ablation of atrial fibrillation using the second-generation cryoballoon versus open-irrigated radiofrequency: results of a multicenter analysis</title><author>Aryana, Arash ; Singh, Sheldon M. ; Mugnai, Giacomo ; de Asmundis, Carlo ; Kowalski, Marcin ; Pujara, Deep K. ; Cohen, Andrew I. ; Singh, Steve K. ; Fuenzalida, Charles E. ; Prager, Nelson ; Bowers, Mark R. ; O’Neill, Padraig Gearoid ; Brugada, Pedro ; d’Avila, André ; Chierchia, Gian-Battista</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-e072d920476ab43db4462096dc82b1da48e799b838d1a9d2c647e6672e89311e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Atrial Fibrillation - diagnosis</topic><topic>Atrial Fibrillation - epidemiology</topic><topic>Atrial Fibrillation - surgery</topic><topic>Cardiology</topic><topic>Catheter Ablation - instrumentation</topic><topic>Catheter Ablation - utilization</topic><topic>Cryosurgery - instrumentation</topic><topic>Cryosurgery - utilization</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Female</topic><topic>Heart Conduction System - surgery</topic><topic>Humans</topic><topic>Incidence</topic><topic>Internationality</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Operative Time</topic><topic>Prevalence</topic><topic>Pulmonary Veins - surgery</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Therapeutic Irrigation - utilization</topic><topic>Treatment Failure</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aryana, Arash</creatorcontrib><creatorcontrib>Singh, Sheldon M.</creatorcontrib><creatorcontrib>Mugnai, Giacomo</creatorcontrib><creatorcontrib>de Asmundis, Carlo</creatorcontrib><creatorcontrib>Kowalski, Marcin</creatorcontrib><creatorcontrib>Pujara, Deep K.</creatorcontrib><creatorcontrib>Cohen, Andrew I.</creatorcontrib><creatorcontrib>Singh, Steve K.</creatorcontrib><creatorcontrib>Fuenzalida, Charles E.</creatorcontrib><creatorcontrib>Prager, Nelson</creatorcontrib><creatorcontrib>Bowers, Mark R.</creatorcontrib><creatorcontrib>O’Neill, Padraig Gearoid</creatorcontrib><creatorcontrib>Brugada, Pedro</creatorcontrib><creatorcontrib>d’Avila, André</creatorcontrib><creatorcontrib>Chierchia, Gian-Battista</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of interventional cardiac electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aryana, Arash</au><au>Singh, Sheldon M.</au><au>Mugnai, Giacomo</au><au>de Asmundis, Carlo</au><au>Kowalski, Marcin</au><au>Pujara, Deep K.</au><au>Cohen, Andrew I.</au><au>Singh, Steve K.</au><au>Fuenzalida, Charles E.</au><au>Prager, Nelson</au><au>Bowers, Mark R.</au><au>O’Neill, Padraig Gearoid</au><au>Brugada, Pedro</au><au>d’Avila, André</au><au>Chierchia, Gian-Battista</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary vein reconnection following catheter ablation of atrial fibrillation using the second-generation cryoballoon versus open-irrigated radiofrequency: results of a multicenter analysis</atitle><jtitle>Journal of interventional cardiac electrophysiology</jtitle><stitle>J Interv Card Electrophysiol</stitle><addtitle>J Interv Card Electrophysiol</addtitle><date>2016-12-01</date><risdate>2016</risdate><volume>47</volume><issue>3</issue><spage>341</spage><epage>348</epage><pages>341-348</pages><issn>1383-875X</issn><eissn>1572-8595</eissn><abstract>Purpose
Catheter ablation of atrial fibrillation (CAAF) using the cryoballoon has emerged as an alternate strategy to point-by-point radiofrequency. However, there is little comparative data on long-term durability of pulmonary vein (PV) isolation comparing these two modalities.
Methods
In this multicenter, retrospective analysis, the incidences/patterns of late PV reconnection following an index CAAF using the second-generation cryoballoon versus open-irrigated, non-force-sensing radiofrequency were examined.
Results
Of the 2002 patients who underwent a first-time CAAF, 186/1126 patients (16.5 %) ablated using cryoballoon and 174/876 patients (19.9 %) with non-contact force-guided radiofrequency required a repeat procedure at 11 ± 5 months. During follow-up, the incidence of atrial flutters/tachycardias was lower (19.9 vs. 32.8 %;
p
= 0.005) and fewer patients exhibited PV reconnection (47.3 vs. 60.9 %;
p
= 0.007) with cryoballoon versus radiofrequency. Additionally, fewer PVs had reconnected with cryoballoon versus radiofrequency (18.8 vs. 34.6 %;
p
< 0.001). With cryoballoon, the right inferior (
p
< 0.001) and left common (
p
= 0.039) PVs were more likely to exhibit late reconnection, versus the left superior PV with radiofrequency (
p
= 0.012). However, when comparing the two strategies, the left common PV was more likely to exhibit reconnection with cryoballoon, whereas all other PVs with the exception of the right inferior PV demonstrated a lower reconnection rate with cryoballoon versus radiofrequency. Lastly, in a logistic regression multivariate analysis, cryoballoon ablation and PV ablation time emerged as significant predictors of durable PV isolation at repeat procedure.
Conclusions
In this large multicenter, retrospective analysis, CAAF using the second-generation cryoballoon was associated with improved durability of PV isolation compared to open-irrigated, non-force-sensing radiofrequency.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>27475949</pmid><doi>10.1007/s10840-016-0172-z</doi><tpages>8</tpages></addata></record> |
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source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | Atrial Fibrillation - diagnosis Atrial Fibrillation - epidemiology Atrial Fibrillation - surgery Cardiology Catheter Ablation - instrumentation Catheter Ablation - utilization Cryosurgery - instrumentation Cryosurgery - utilization Equipment Design Equipment Failure Analysis Female Heart Conduction System - surgery Humans Incidence Internationality Male Medicine Medicine & Public Health Middle Aged Operative Time Prevalence Pulmonary Veins - surgery Recurrence Risk Factors Therapeutic Irrigation - utilization Treatment Failure Treatment Outcome |
title | Pulmonary vein reconnection following catheter ablation of atrial fibrillation using the second-generation cryoballoon versus open-irrigated radiofrequency: results of a multicenter analysis |
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