The Rapid Induction of Carbapenem-Resistance in an Aeromonas dhakensis Blood Isolate

Meropenem-susceptible and -resistant Aeromonas dhakensis isolates from blood cultures of a fatal case of septicemia were analyzed. The two isolates were homologous and gene expression of metallo-β-lactamase in the resistant strain was upregulated. Physicians should be aware of the possibility of the...

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Veröffentlicht in:	Japanese Journal of Infectious Diseases 2016, Vol.69(5), pp.439-441
Hauptverfasser:	Murata, Mika, Morinaga, Yoshitomo, Akamatsu, Norihiko, Matsuda, Junichi, Uno, Naoki, Kosai, Kosuke, Hasegawa, Hiroo, Okada, Masahiko, Moriuchi, Hiroyuki, Yanagihara, Katsunori
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Aeromonas - drug effects Aeromonas - isolation & purification Aeromonas dhakensis Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Bacteremia - microbiology beta-Lactam Resistance beta-Lactamases - biosynthesis beta-Lactamases - genetics Blood - microbiology carbapenem-resistance Female Gene Expression Profiling Gram-Negative Bacterial Infections - microbiology Humans Male meropenem Middle Aged septicemia Thienamycins - pharmacology Time Factors Up-Regulation
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Zusammenfassung:	Meropenem-susceptible and -resistant Aeromonas dhakensis isolates from blood cultures of a fatal case of septicemia were analyzed. The two isolates were homologous and gene expression of metallo-β-lactamase in the resistant strain was upregulated. Physicians should be aware of the possibility of the induction of carbapenem-resistance, following the use of carbapenems in the treatment of Aeromonas infection.
ISSN:	1344-6304 1884-2836
DOI:	10.7883/yoken.JJID.2015.098