Axial length measurement failure rates with biometers using swept source optical coherence tomography compared to partial coherence interferometry and optical low-coherence interferometry

Abstract Purpose To compare a new swept source optical coherence tomography (SS-OCT) based biometer (OA-2000) with the IOLMaster v5.4 (partial coherence interferometry) and Aladdin (optical low-coherence interferometry) biometers in terms of axial length measurement and failure rate in eyes with cataract. Design Reliability study Methods A total of 377 eyes of 210 patients were scanned with the three biometers in a random order. For each biometer, the number of unobtainable axial length measurements was recorded and grouped as per the type and severity of cataract based on the Lens Opacities Classification System III by the same experienced ophthalmologist. The Bland-Altman limits of agreement (LoA) method was used to assess the agreement in axial length measurements between the three biometers. Results The failure rate was 0 eyes (0%) with the OA-2000, 136 eyes (36.07%) with the IOLMaster and 51 eyes (13.53%) with the Aladdin. Chi-squared analyses indicated a significant difference in failure rate between all three devices (P