Pleomorphic adenoma and adenoid cystic carcinoma of salivary glands: E-cadherin immunoexpression and analysis of the CDH1 −160C/A polymorphism

Highlights • E-cadherin expression in PA and ACC is mainly related to cellular composition (epithelial cells versus myoepithelial cells) and the degree of differentiation of myoepithelial cells. • The CDH1 −160C/A polymorphism does not seem to significantly influence the expression of E-cadherin in...

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Veröffentlicht in:	Archives of oral biology 2017-01, Vol.73, p.48-54
Hauptverfasser:	Cavalcante, Roberta Barroso, DDS, PhD, Nonaka, Cassiano Francisco Weege, DDS, PhD, Rabenhorst, Silvia Helena Barem, PhD, Miguel, Márcia Cristina da Costa, DDS, PhD, Pinto, Leão Pereira, DDS, PhD, Souza, Lélia Batista de, DDS, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoid cystic carcinoma Adenoma, Pleomorphic - genetics Adenoma, Pleomorphic - metabolism Advanced Basic Science Cadherins - genetics Cadherins - metabolism Carcinoma, Adenoid Cystic - genetics Carcinoma, Adenoid Cystic - metabolism CDH1 gene Dentistry E-Cadherin Electrophoresis, Polyacrylamide Gel Genotype Humans Immunoenzyme Techniques Pleomorphic adenoma Polymerase Chain Reaction Polymorphism Polymorphism, Genetic Polymorphism, Restriction Fragment Length Salivary Gland Neoplasms - genetics Salivary Gland Neoplasms - metabolism
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Zusammenfassung:	Highlights • E-cadherin expression in PA and ACC is mainly related to cellular composition (epithelial cells versus myoepithelial cells) and the degree of differentiation of myoepithelial cells. • The CDH1 −160C/A polymorphism does not seem to significantly influence the expression of E-cadherin in PA and ACC of salivary glands.
ISSN:	0003-9969 1879-1506
DOI:	10.1016/j.archoralbio.2016.09.005