A highly enantioselective synthesis of (R)-salmeterol using a chiral auxiliary
A facile strategy for enantioselective synthesis of (R)-salmeterol is described via a chiral auxiliary starting from 2-bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanone through four or five steps. The product was obtained in good purity, enantiomeric excess and yield.
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| Veröffentlicht in: | Journal of chemical research 2016-09, Vol.40 (9), p.564-566 |
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| container_end_page | 566 |
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| container_issue | 9 |
| container_start_page | 564 |
| container_title | Journal of chemical research |
| container_volume | 40 |
| creator | Jiang, Lijue Lin, Chenggang Qiu, Yinhua Quan, Xu Zhu, Jing Shi, Haijian |
| description | A facile strategy for enantioselective synthesis of (R)-salmeterol is described via a chiral auxiliary starting from 2-bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanone through four or five steps. The product was obtained in good purity, enantiomeric excess and yield. |
| doi_str_mv | 10.3184/174751916X14719559894647 |
| format | Article |
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| ispartof | Journal of chemical research, 2016-09, Vol.40 (9), p.564-566 |
| issn | 1747-5198 2047-6507 |
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| subjects | Purity Strategy Synthesis |
| title | A highly enantioselective synthesis of (R)-salmeterol using a chiral auxiliary |
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