A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues
A biotin appended formaldehyde sensor was found to specifically visualise both exogenous and endogenous levels of formaldehyde in biotin receptor positive cells over biotin negative cells by means of one- and two-photon excitation. The probe furthermore visualised endogenous levels of formaldehyde i...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2016-09, Vol.52 (75), p.11247-1125 |
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| container_title | Chemical communications (Cambridge, England) |
| container_volume | 52 |
| creator | Lee, Yun Hak Tang, Yonghe Verwilst, Peter Lin, Weiying Kim, Jong Seung |
| description | A biotin appended formaldehyde sensor was found to specifically visualise both exogenous and endogenous levels of formaldehyde in biotin receptor positive cells over biotin negative cells by means of one- and two-photon excitation. The probe furthermore visualised endogenous levels of formaldehyde in tumour tissue slices up to 70 μm depth.
A biotin appended formaldehyde sensor was found to visualise exogenous and endogenous formaldehyde levels in living cells and tumour tissues. |
| doi_str_mv | 10.1039/c6cc06158c |
| format | Article |
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The probe furthermore visualised endogenous levels of formaldehyde in tumour tissue slices up to 70 μm depth.
A biotin appended formaldehyde sensor was found to visualise exogenous and endogenous formaldehyde levels in living cells and tumour tissues.</abstract><cop>England</cop><pmid>27722498</pmid><doi>10.1039/c6cc06158c</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-4673-2050</orcidid></addata></record> |
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| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2016-09, Vol.52 (75), p.11247-1125 |
| issn | 1359-7345 1364-548X |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Animals Biotin Biotin - chemistry Cell Line, Tumor Excitation Fluorescent Dyes - chemistry Formaldehyde Formaldehyde - analysis Formaldehyde - chemistry Humans Imaging, Three-Dimensional Mice Microscopy, Confocal Neoplasms - chemistry Neoplasms - metabolism Neoplasms - pathology NIH 3T3 Cells Optical Imaging Photons Receptors Sensors Spectrometry, Fluorescence Tumors |
| title | A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues |
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