A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron( iii )-catalysis

A selective, catalytic and practical method for removing a Boc group from several N , N ′-diprotected amino acids and amine derivatives using iron( iii ) salts as sustainable catalysts is described. The process is clean, not needing a purification step. A theoretical study rationalizing the results with several metals is presented.