Persistent elevation of aspartate aminotransferase (AST) due to the presence of macro-AST: Report of one case

Persistent elevation of aspartate aminotransferase (AST) due to the presence of macro-AST: Report of one case

We report an asymptomatic 23-year-old woman with an isolated and persistent increase in serum levels of aspartate aminotransferase (AST). An extensive work up including laboratory and image testing revealed no abnormalities thus suggesting the presence of macro-AST. A polyethylene glycol (PEG) preci...

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Veröffentlicht in:Revista medíca de Chile 2016-08, Vol.144 (8), p.1078-1082
Hauptverfasser: Bustamante, Verónica, Arab, Juan Pablo, Terc, Florencia, Poggi, Helena, Goycoolea, Manuela, Arrese, Marco, Quiroga, Teresita, Benítez, Carlos
Format: Artikel
Sprache:spa
Schlagworte:
Alanine Transaminase - blood
Aspartate Aminotransferases - blood
Autoimmune Diseases - diagnosis
Autoimmune Diseases - enzymology
Female
Humans
Liver Diseases - diagnosis
Liver Diseases - enzymology
Young Adult
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Zusammenfassung:We report an asymptomatic 23-year-old woman with an isolated and persistent increase in serum levels of aspartate aminotransferase (AST). An extensive work up including laboratory and image testing revealed no abnormalities thus suggesting the presence of macro-AST. A polyethylene glycol (PEG) precipitation assay was performed and confirmed the presence of macro-AST.
ISSN:0717-6163
DOI:10.4067/S0034-98872016000800017