Differential Patterns of Impaired Cardiorespiratory Fitness and Cardiac Autonomic Dysfunction in Recently Diagnosed Type 1 and Type 2 Diabetes

Both impaired cardiorespiratory fitness (CRF) and heart rate variability (HRV) are predictors of mortality, but their relative roles in recent-onset diabetes are unknown. We determined to which extent CRF and HRV are reduced and interrelated in recent-onset diabetes. Participants from the German Dia...

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Veröffentlicht in:Diabetes care 2017-02, Vol.40 (2), p.246-252
Hauptverfasser: Röhling, Martin, Strom, Alexander, Bönhof, Gidon, Püttgen, Sonja, Bódis, Kálmán, Müssig, Karsten, Szendrödi, Julia, Markgraf, Daniel, Lehr, Stefan, Roden, Michael, Ziegler, Dan
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Sprache:eng
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Zusammenfassung:Both impaired cardiorespiratory fitness (CRF) and heart rate variability (HRV) are predictors of mortality, but their relative roles in recent-onset diabetes are unknown. We determined to which extent CRF and HRV are reduced and interrelated in recent-onset diabetes. Participants from the German Diabetes Study with type 1 (n = 163) or type 2 (n = 188) diabetes with known diabetes duration 0.34; P < 0.05) but not in those with type 2 diabetes. CRF is reduced in recently diagnosed type 2 diabetes but preserved in type 1 diabetes, whereas cardiac autonomic function is reduced in both diabetes types but is strongly associated with CRF only in type 1 diabetes. These results support the therapeutic concept of promoting physical fitness in the early course of diabetes.
ISSN:0149-5992
1935-5548
DOI:10.2337/dc16-1898