An Atypical Withdrawal Syndrome in Neonates Prenatally Exposed to Gabapentin and Opioids

We report a retrospective case series of 19 infants exposed to both opioids and gabapentin prenatally. We describe a unique behavioral phenotype in 15 of these infants and report a treatment strategy.

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of pediatrics 2017-02, Vol.181, p.286-288
Hauptverfasser:	Loudin, Sean, MD, Murray, Sara, RN, Prunty, Leesa, PharmD, Davies, Todd, PhD, Evans, Joseph, MD, Werthammer, Joseph, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines - adverse effects Amines - therapeutic use Analgesics, Opioid - adverse effects Analgesics, Opioid - therapeutic use co-exposure Cyclohexanecarboxylic Acids - adverse effects Cyclohexanecarboxylic Acids - therapeutic use Female gabapentin gamma-Aminobutyric Acid - adverse effects gamma-Aminobutyric Acid - therapeutic use Humans Infant Infant, Newborn Methadone - therapeutic use NAS Neonatal Abstinence Syndrome - drug therapy neonatology opioids Pediatrics Pregnancy Prenatal Exposure Delayed Effects - epidemiology Retrospective Studies withdrawal
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Beschreibung
Zusammenfassung:	We report a retrospective case series of 19 infants exposed to both opioids and gabapentin prenatally. We describe a unique behavioral phenotype in 15 of these infants and report a treatment strategy.
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2016.11.004